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Noninvasive Brain Stimulation in Mild Cognitive Impairment and Dementia

NCT05270408 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 33

Last updated 2025-03-05

Study results available
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Summary

The research objective of this study is to examine the efficacy of HD-tDCS to the preSMA/DACC region and its influence on verbal episodic memory in patients with MCI or dementia after 10 sessions of HD-tDCS. There will be three treatment arms: two active HD-tDCS (1 mA or 2 mA) and a sham group. A verbal episodic memory task will be completed at baseline, immediately following the last HD-tDCS session, and a 2-month follow-up.

Conditions

Interventions

DEVICE

Active Transcranial direct current stimulation (STARStim 8)

Participants wear a neoprene cap on their head and electrodes filled with gel are attached and will deliver 1mA to the scalp.

DEVICE

Active Transcranial direct current stimulation (STARStim 8)

Participants wear a neoprene cap on their head and electrodes filled with gel are attached and will deliver 2mA to the scalp.

DEVICE

Sham Transcranial direct current stimulation (STARStim 8)

Participants wear a neoprene cap on their head and electrodes filled with gel are attached and will deliver no current to the scalp.

Sponsors & Collaborators

  • University of Texas Southwestern Medical Center

    lead OTHER

Principal Investigators

  • Christian LoBue, PhD · UT Southwestern Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-07-13
Primary Completion
2024-02-15
Completion
2024-02-15
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05270408 on ClinicalTrials.gov