Optimizing Detection and Prediction of Changes in Cognitive Function in Multiple Sclerosis (MS)
NCT05252195 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 300
Last updated 2025-04-27
Summary
The researchers will use technology-assisted ambulatory assessment techniques to examine cognitive dysfunction in people with Multiple Sclerosis (MS).
The researchers will determine if ambulatory assessments are sensitive to subtle declines in cognitive functioning. They will also explore the impact of modifiable factors, such as sleep, physical activity, mood, and somatic symptoms on cognitive function. These efforts will uncover behavioral and medical intervention methods. Finally, they will explore whether variability in cognitive functioning predicts short- and long-term changes in other patient-centered functional domains, social participation and physical functioning.
Conditions
Sponsors & Collaborators
-
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
collaborator NIH -
Wayne State University
collaborator OTHER - collaborator OTHER
- lead OTHER
Principal Investigators
-
Anna Kratz · University of Michigan
-
Nora Fritz · Wayne State University
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-05-24
- Primary Completion
- 2027-03-31
- Completion
- 2027-03-31
Countries
- United States
Study Locations
More Related Trials
-
Impact of Neuropsychological Disorders in Multiple Sclerosis
NCT04837365 ·Status: COMPLETED ·Phase: NA
-
Evaluation and Neural Basis of Communication in Patients With Multiple Sclerosis
NCT02652013 ·Status: COMPLETED ·Phase: NA
-
Emotional and Change-related Attention in Autism
NCT02160119 ·Status: COMPLETED
-
Dual Task Cost in the Upper Limb in Persons With Multiple Sclerosis
NCT02493166 ·Status: COMPLETED ·Phase: NA
-
Nature of the Link Between Executive Functions and Theory of Mind in Multiple Sclerosis
NCT04806217 ·Status: UNKNOWN ·Phase: NA
-
Effects of Training on Central Auditory Function in Multiple Sclerosis
NCT01023074 ·Status: COMPLETED ·Phase: NA
-
Walking and Thinking - Brain Activity During Complex Walking in People With Multiple Sclerosis
NCT05787704 ·Status: COMPLETED
-
Impaired Glucose Tolerance and Cognition in MS
NCT04748302 ·Status: TERMINATED
-
Upper Airway Function and Cardiorespiratory Performance in Impair Trunk Motor Control Multiple Sclerosis Patients.
NCT04252599 ·Status: UNKNOWN
-
Neurophysiology of Surround Inhibition in the Human Motor Cortex
NCT03018262 ·Status: COMPLETED
-
Non-invasive Cerebellar Stimulation on Motor Learning
NCT02559518 ·Status: COMPLETED ·Phase: NA
-
Resting Postural Tremor in Multiple Sclerosis
NCT04405479 ·Status: RECRUITING
-
Early Diagnosis of Patients With Mild Cognitive Impairment Through the Parameterization of Functional Tests.
NCT03851198 ·Status: WITHDRAWN ·Phase: NA
-
Motor Evoked Potentials With Modified Facilitation Technique
NCT03646929 ·Status: COMPLETED ·Phase: NA
-
Brain Function in Performance of Motor Tasks
NCT00498329 ·Status: COMPLETED
-
Auditory-motor Coupling in Multiple Sclerosis With Cerebellar Lesions
NCT04639401 ·Status: COMPLETED ·Phase: NA
-
Sleep Disorders and Quality of Life in Patients With Multiple Sclerosis
NCT06012513 ·Status: NOT_YET_RECRUITING
-
Conventional Vestibular Training Versus Immersive Virtual Reality- Based Vestibular in Multiple Sclerosis
NCT04497025 ·Status: WITHDRAWN ·Phase: NA
-
Detecting a Reward Signal in the Motor Cortex
NCT00422071 ·Status: COMPLETED
-
To Explore the Neural Processing Mechanism of Cerebellum Involved in Facial Expression Recognition Based on Transcranial Magnetic Stimulation
NCT06860451 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Edinburgh Cognitive and Behavioural Amyotrophic Lateral Sclerosis Screen in Norway: A Validation Study
NCT03579017 ·Status: COMPLETED
-
Cognitive Assessment by the Mean of Event Related Potentials
NCT01899924 ·Status: UNKNOWN ·Phase: NA
-
Onset of Lower Urinary Tract Symptoms in Multiple Sclerosis Patients
NCT06226831 ·Status: RECRUITING
-
Effect of Variance on Error Correction During Coupling
NCT04856384 ·Status: COMPLETED ·Phase: NA
-
Cognitive Function Assessment in Patients With Focal Brain Injury
NCT04182087 ·Status: RECRUITING