MedTrace Logo

Prognostic Impact of Lesion-specific Hemodynamic Index in Patients With Coronary Artery Disease

NCT05250557 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 2429

Last updated 2022-02-22

No results posted yet for this study

Summary

The investigators aim to investigate the additive prognostic value of lesion-specific hemodynamic index such as ΔFFR, non-hyperemic pressure ratio such as RFR, over % diameter stenosis and FFR according to treatment strategy, and to find the prognostic implications of post-PCI FFR after adjustment of various clinical and disease characteristics, and to construct a comprehensive risk prediction model for post-PCI outcomes.

Conditions

Interventions

DIAGNOSTIC_TEST

Fractional flow reserve

Physiologic assessment includes Δ FFR (lesion-specific) and FFR (vessel-specific) measurement. Δ FFR is defined as a pressure step up across the lesion. Coronary angiography and physiologic assessment will be analyzed by an independent core laboratory (Seoul National University Hospital, Clinical Trial Center, Seoul, South Korea).

Sponsors & Collaborators

  • Keimyung University Dongsan Medical Center

    collaborator OTHER

  • Inje University

    collaborator OTHER

  • Ulsan University Hospital

    collaborator OTHER

  • Dong-A University Hospital

    collaborator OTHER

  • Gyeongsang National University Hospital

    collaborator OTHER

  • KangWon National University Hospital

    collaborator OTHER

  • Wonju Severance Christian Hospital

    collaborator OTHER

  • Severance Hospital

    collaborator OTHER

  • Seoul National University Bundang Hospital

    collaborator OTHER

  • Tsuchiura Kyodo General Hospital

    collaborator OTHER

  • Seoul National University Hospital

    lead OTHER

Principal Investigators

  • Bon-Kwon Koo, MD, PhD · Seoul National University Hospital

Eligibility

Min Age
20 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-08-01
Primary Completion
2025-12-31
Completion
2026-12-31

Countries

  • South Korea

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05250557 on ClinicalTrials.gov