Circulating Biomarkers in Patients With Anal Cancer Treated With Induction Chemotherapy
NCT05233540 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2022-02-10
Summary
To investigate the prognostic and predictive value of plasma HPV (pHPV) prior, during and after induction chemotherapy (ICT) in locally advanced squamous cell carcinoma of the anus (SCCA) or synchronous metastatic SCCA patients treated with ICT prior to definitive (chemo)radiotherapy ((C)RT) according to multidisciplinary team (MDT) conferences based decisions. Further to investigate the use of pHPV measurements and other relevant markers for prediction of response and survival after ICT prior to definitive (C)RT.
Conditions
- Anal Cancer
- Locally Advanced Squamous Cell Carcinoma
- Oligometastatic Disease
- Circulating Tumor Cell
- Human Papilloma Virus
Sponsors & Collaborators
-
Aarhus University Hospital
lead OTHER
Principal Investigators
-
Karen L Wind, MD · Aarhus University Hospital
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-01-01
- Primary Completion
- 2023-12-31
- Completion
- 2025-12-31
Countries
- Denmark
Study Locations
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