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Circulating Tumor Cells in Patients With Locally Advanced Rectal Cancer

NCT02874885 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 341

Last updated 2026-03-11

No results posted yet for this study

Summary

This study looks at the level of circulating tumor elements (cancer cells or DNA pieces floating in the blood) and how it may be related to how the tumor responds to standard treatment in patients with rectal cancer that has spread to nearby tissue or lymph nodes (locally advanced). Researchers will also compare the level and genetic characteristics of circulating tumor elements between individuals with rectal cancer and healthy individuals to understand how they may change over time. Information from this study may help researchers better understand rectal cancer.

Conditions

  • Locally Advanced Rectal Adenocarcinoma
  • Metastatic Rectal Adenocarcinoma
  • Rectosigmoid Adenocarcinoma
  • Recurrent Rectal Adenocarcinoma
  • Recurrent Rectosigmoid Carcinoma
  • Stage III Rectal Cancer AJCC v8
  • Stage IIIA Rectal Cancer AJCC v8
  • Stage IIIB Rectal Cancer AJCC v8
  • Stage IIIC Rectal Cancer AJCC v8
  • Stage IV Rectal Cancer AJCC v8
  • Stage IVA Rectal Cancer AJCC v8
  • Stage IVB Rectal Cancer AJCC v8
  • Stage IVC Rectal Cancer AJCC v8

Interventions

PROCEDURE

Biospecimen Collection

Undergo collection of blood sample

Sponsors & Collaborators

  • M.D. Anderson Cancer Center

    lead OTHER

Principal Investigators

  • Yi-Qian N You · M.D. Anderson Cancer Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-09-05
Primary Completion
2027-04-30
Completion
2027-04-30

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02874885 on ClinicalTrials.gov