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Comparison of the Effect of Gingival Massage of Aloe-vera Gel and Sidr Honey on Chronic Periodontitis

NCT05231096 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 105

Last updated 2022-02-25

No results posted yet for this study

Summary

Chronic Periodontitis is an inflammatory condition and a common disease worldwide. Honey has been used in dentistry for its beneficial properties. It has been used in many oral conditions like gingivitis and periodontal diseases for its antibacterial and healing properties, on the other hand, aloe vera gel is known for its anti-inflammatory aspects, and it has been used in dentistry for its potential advantages.

Objective The main objective of the study was to find out the effects of gingival massage with aloe-vera gel and sidr honey as adjunct to non surgical therapy after one month in patients with Chronic periodontitis and to find out whether there is a difference in the efficacy of aloe-vera gel and sidr honey in reducing plaque index, gingival index, pocket depth and bleeding on probing after one month of gingival massage when used as adjunct to non-surgical therapy.

Method 105 patients with chronic periodontitis were selected in this single-blinded Randomized control clinical trial. At recruitment non-surgical therapy i-e scaling and root debridement was performed. At baseline all clinical parameters, gingival index, plaque index, bleeding on probing and pocket depths were recorded. All the participants were then randomly divided in three groups, Group A: SRD \& Gingival massage with Aloe-vera gel, Group B: SRD \& Gingival massage with Sidr honey and Group C SRD only. On 30th day of trial all the patients were re-examined for all the clinical parameters.

Statistical Analysis SPSS version 21 was used for data entry and analysis with significance level set at Ƥ \<0.05. Median, median difference and Inter Quartile ranges were reported for plaque index, gingival index, probing depth and percentages were reported for bleeding on probing. Wilcoxon Signed rank test was used for pre and post comparison. Mann Whitney test was applied for comparison between groups.

Conditions

  • Gingival Massage
  • Chronic Periodontitis

Interventions

OTHER

Aloe-vera gel

Aloe-Vera gel Production Aloe vera gel used in this study was 98% aloe vera gel concentration and 2% normal saline. Preparation of aloe-vera gel consists of ripen leaf of aloe vera.(26) Aloe vera leaf was washed thoroughly under water and then cut from the center and the seeping gel was collected in sterile container and was stored at 4°C until the time of application. In our research this pure Aloe vera gel was extracted by The Pakistan Council of Scientific \& Industrial Research (PCSIR) laboratory.

OTHER

sidr honey

Honey collection Sidr (Beri) honey was used in this study. Honey was thick, raw and cold extracted from remote Pakistan afghan tribal forest belt of Sidr trees. It was smooth, viscous and medium to dark amber in color.

PROCEDURE

Scaling ans root Debridement

non-surgical periodontal therapy was given to all the participants of all the three groups

Sponsors & Collaborators

  • Dow University of Health Sciences

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
35 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-09-03
Primary Completion
2020-06-12
Completion
2020-10-15

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05231096 on ClinicalTrials.gov