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Mapping the Human Appendix Using Single Cell Sequencing

NCT05209061 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 5

Last updated 2023-02-08

No results posted yet for this study

Summary

The overall purpose of this study is to describe the cellular composition of the human appendix and its gene expression using scRNAseq and scATACseq methods. This will potentially provide is with a complete and detailed map of the appendix´ immunological properties and its role in neuro-endocrine/metabolic functions. Our results will be held up against current knowledge of the appendix and its role in the human body and thus hopefully expand our understanding of this organ and the consequences of its removal by appendectomy.

Conditions

  • Diabetes
  • Appendicitis
  • Inflammatory Bowel Diseases

Interventions

OTHER

Biopsy

Participants included in the study, will have a full thickness biopsy of the middle of the appendix taken, after the resected bowel has been removed during surgery.

Sponsors & Collaborators

  • The Novo Nordisk Foundation Center for Basic Metabolic Research

    collaborator OTHER

  • Bispebjerg Hospital

    lead OTHER

Principal Investigators

  • Jacob Antonsen, MD · Bispebjerg Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-02-01
Primary Completion
2023-12-30
Completion
2024-06-01

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05209061 on ClinicalTrials.gov