VIGOR: Virtual Genome Center for Infant Health

Summary

This study will provide rigorous evaluation of implementing a virtual genome center into community clinical settings without highly specialized resources, thereby offering generalizable insights as to how best to implement genomic medicine at scale and for other age groups. This intervention has great potential to address disparities in genomic medicine among low-income and underrepresented minority (URM) populations and will enhance capacity for providers and health systems to utilize highly specialized genomic techniques in their communities.

The goal of this study is to achieve equitable access to state-of-the-art genomic medical care to sick newborns in community centers that predominately care for low-income and racial/ethnic minority populations through the creation of a virtual genome center (VIGOR). VIGOR will provide a venue for physician and family education, genomic expert consultation, reanalysis of unsolved sequencing data, and access to cutting edge therapeutic innovation, thereby facilitating institutionalization of genomic best practices in community settings, and not just highly specialized referral centers.

Conditions

• Genetics Disease
• Genetics/Birth Defects
• Genetic Predisposition to Disease

Sponsors & Collaborators

• Boston Medical Center

  collaborator OTHER

• Baystate Medical Center

  collaborator OTHER

• UMass Memorial Health

  collaborator OTHER

• The Cooper Health System

  collaborator OTHER

• National Human Genome Research Institute (NHGRI)

  collaborator NIH

• DHR Health Institute for Research and Development

  collaborator OTHER

• The Hospitals of Providence East Campus

  collaborator UNKNOWN

• The Hospitals of Providence Memorial Campus

  collaborator UNKNOWN

• Jackson Health System

  collaborator OTHER

• University of Texas

  collaborator OTHER

• Driscoll Children's Hospital

  collaborator OTHER

• University of South Alabama

  collaborator OTHER

• Boston Children's Hospital

  lead OTHER

Principal Investigators

• Timothy Yu, MD, PhD · Boston Children's Hospital

Eligibility

Min Age

0 Days

Max Age

99 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2022-03-22

Primary Completion

2026-11-30

Completion

2027-03-01

Countries

• United States

Study Locations