Early Antiplatelet for Minor Stroke Following Thrombolysis (EAST)
NCT05193071 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 1022
Last updated 2024-10-31
Summary
The current guideline recommends to give antithrombotic treatment 24 hours after intravenous thrombolysis in acute ischemic stroke. However, early neurological deterioration will occur in some patients due to no antithrombotic treatment, which is closely associated with poor outcome. The current trial aims to investigate the effectiveness and safety of early antithrombotic treatment after intravenous thrombolysis in minor stroke.
Conditions
Interventions
- DRUG
-
Aspirin 100mg; Clopidogrel 300mg
Aspirin 100mg plus Clopidogrel 300mg will be orally administrated after randomization
Sponsors & Collaborators
-
General Hospital of Shenyang Military Region
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-07-08
- Primary Completion
- 2024-10-25
- Completion
- 2024-10-25
Countries
- China
Study Locations
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