Prognostic Accuracy of qSOFA, SIRS, and EWSs for In-hospital Mortality in Emergency Department
NCT05172479 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 3274
Last updated 2023-09-13
Summary
Early identification of a patient with infection who may develop sepsis is of utmost importance. Unfortunately, this remains elusive because no single clinical measure or test can reflect complex pathophysiological changes in patients with sepsis. However, multiple clinical and laboratory parameters indicate impending sepsis and organ dysfunction. Screening tools using these parameters can help identify the condition, such as SIRS, quick SOFA (qSOFA), National Early Warning Score (NEWS), or Modified Early Warning Score (MEWS). The 2016 SCCM/ESICM task force recommended using qSOFA, while the 2021 Surviving Sepsis Campaign strongly recommended against its use compared with SIRS, NEWS, or MEWS as a single screening tool for sepsis or septic shock. We hypothesised that qSOFA has greater prognostic accuracy than SIRS and EWS (NEWS/NEWS2/MEWS).
Conditions
- Sepsis
- Septic Shock
Interventions
- DIAGNOSTIC_TEST
-
Measurement of qSOFA score
At the patient's arrival to the ED triage, the nurse will enter the patient's vital signs data into electronic data capture (EDC) system that will calculate the patient's qSOFA score.
- DIAGNOSTIC_TEST
-
Measurement of SIRS criteria
At the patient's arrival to the ED triage, the nurse will enter the patient's vital signs data into electronic data capture (EDC) system that will calculate the patient's SIRS criteria.
- DIAGNOSTIC_TEST
-
Measurement of NEWS
At the patient's arrival to the ED triage, the nurse will enter the patient's vital signs data into electronic data capture (EDC) system that will calculate the patient's NEWS.
- DIAGNOSTIC_TEST
-
Measurement of NEWS2
At the patient's arrival to the ED triage, the nurse will enter the patient's vital signs data into electronic data capture (EDC) system that will calculate the patient's NEWS2.
- DIAGNOSTIC_TEST
-
Measurement of MEWS
At the patient's arrival to the ED triage, the nurse will enter the patient's vital signs data into electronic data capture (EDC) system that will calculate the patient's MEWS.
Sponsors & Collaborators
-
Armed Force Hospital Southern Region-Khamis Mushayt (AFHSR-KM)
collaborator UNKNOWN -
King Khalid University (KKU)
collaborator UNKNOWN -
Aseer Central Hospital
lead OTHER_GOV
Principal Investigators
-
Abdullah M Algarni, MBBS · Aseer Central Hospital (ACH)
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-12-12
- Primary Completion
- 2023-09-11
- Completion
- 2023-09-11
Countries
- Bahrain
- Kuwait
- Oman
- Qatar
- Saudi Arabia
- Turkey (Türkiye)
- United Arab Emirates
Study Locations
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