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Evaluating Personalized Therapeutics Clinic (PTC) on Drug-Drug Interactions and Drug-Gene Interactions

NCT05166694 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1300

Last updated 2026-03-04

No results posted yet for this study

Summary

The purpose of this study is to determine whether a consultation with a Personalized Therapeutics Clinic, or PTC, will help participants lower the risk for side effects (drug-drug interactions and drug-gene interactions) when taking many medications and help providers improve prescribing decisions for participants. A PTC is a clinical that will test your genes to gather information about your health that may help guide prescribing advice and offer you new information about your prescriptions. Doctors leading this study will look for variations (differences) in your genes that may suggest that you are at greater risk of having side effects or a greater chance of benefiting from certain medications. Individuals in this study will participate for roughly 9 months.

Conditions

Interventions

OTHER

Drug-Drug Interaction Profile

A profile based on genetic testing that shows information about how the participant's medications they are taking interact with each other.

OTHER

Drug-Gene Interaction Profile

A profile based on genetic testing that shows information about how the participant's genes interact with/respond to certain medications they are taking.

OTHER

Standard of Care

The standard treatment and prescribing for the participant's specific type of cancer.

Sponsors & Collaborators

  • University of Chicago

    lead OTHER

Principal Investigators

  • Mark Ratain, MD · University of Chicago

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-11-30
Primary Completion
2027-11-01
Completion
2027-11-01

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05166694 on ClinicalTrials.gov