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Role of Doxycycline in Chronic Rhinosinusitis With Nasal Polyps

NCT05157412 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2024-08-13

No results posted yet for this study

Summary

To evaluate the efficacy of Doxycycline as an adjunct to systemic steroids in the treatment of chronic rhinosinusitis with nasal polyps

Conditions

Interventions

DRUG

Doxycycline 100 mg Oral Tablet

Oral Doxycycline will be added to prednisolone as a comparison to using prednisolone as a sole therapy for the treatment of nasal polyps associated with chronic rhinosinusitis

DRUG

Prednisolone 20 mg

Prednisolone will be used in both arms as a sole therapy in one and together with doxycycline in the other

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Mai AbuElmagd · Assiut University

  • Hamza El Shafie · Assiut University

  • Aly Ragaie · Assiut University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-07-01
Primary Completion
2023-09-01
Completion
2024-01-01
FDA Drug
Yes

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05157412 on ClinicalTrials.gov