Gut Microbiota, the Potential Key to Modulating Humoral Immunogenicity of New Platform COVID-19 Vaccines
NCT05150834 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 53
Last updated 2021-12-09
Summary
Vaccination is the best way to mitigate the coronavirus disease 2019 (COVID-19) pandemic, but the vaccine immunogenicity may be quite variable from person to person. There is increasing evidence suggesting that the gut microbiome is a major determinant of vaccine immunogenicity. Thus, the investigators investigated the relationship between gut microbiota and humoral immune response after COVID-19 vaccination.
Conditions
- Microbiome
- Vaccine
- Covid-19
- SARS-CoV-2
- Immunogenicity
Interventions
- OTHER
-
This is observational study
We enrolled the healthcare workers assigned to get either BNT162b2 or ChAdOx1 by the Korean government.
Sponsors & Collaborators
-
Korea University Guro Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-02-25
- Primary Completion
- 2021-07-16
- Completion
- 2023-12-31
Countries
- South Korea
Study Locations
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