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Gut Microbiota, "Spark and Flame" of COVID-19 Disease

NCT04355741 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 115

Last updated 2020-08-25

No results posted yet for this study

Summary

Elderly, hypertension, diabetes and cardiovascular diseases are risk factors for COVID-19 morbility and mortality. However, the real reason for this is not yet understood. It is well documented that gut microbiota has a critical role in health, particularly in the immune system and therefore, we propose that gut microbiota composition could affect vulnerability and disease outcomes of COVID-19.

Conditions

Interventions

OTHER

Exposure

Individuals with SARS-CoV-2 exposure and COVID-19 symptoms.

Sponsors & Collaborators

  • Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental

    collaborator UNKNOWN

  • Centro Hospitalar Universitário São João

    collaborator UNKNOWN

  • CUF Academic and Research Medical Center

    collaborator UNKNOWN

  • Hospital CUF Infante Santo, S.A.

    collaborator UNKNOWN

  • Centro de Medicina Laboratorial Germano de Sousa, S.A.

    collaborator UNKNOWN

  • CINTESIS - Center for Health Technology and Services Research

    collaborator UNKNOWN

  • Universidade Nova de Lisboa

    lead OTHER

Principal Investigators

  • Conceição Calhau, PhD · Universidade Nova de Lisboa

  • Pedro Póvoa, PhD · Hospital São Francisco Xavier

  • Cristina Granja, PhD · Centro Hospitalar Universitário São João

  • Maria JR Sousa, PhD · Centro de Medicina Laboratorial Germano de Sousa, S.A.

  • José Leal, PhD · Centro de Medicina Laboratorial Germano de Sousa, S.A.

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-04-20
Primary Completion
2020-07-01
Completion
2020-07-16

Countries

  • Portugal

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04355741 on ClinicalTrials.gov