EPPIC: Easing Pelvic Pain Interventions Clinical Research Program

Summary

The EPPIC (Easing Pelvic Pain Interventions Clinical Research Program) study evaluates an ultra-brief, 4 session cognitive behavioral pain treatment transdiagnostic in design for urologic chronic pain syndrome (UCPPS) with clinical and practical advantages over existing behavioral therapies whose length and focus limits their adoption by clinicians and coverage for mechanistically similar comorbidities. A theoretically informed, practical, empirically grounded approach will systematically unpack CBT's working mechanisms, clarify for whom it works, ease dissemination, appeal to patients, providers, payers, and policy makers in the COVID-19 era favoring low resource intensity treatments, and reduce cost and inefficiencies associated with high intensity therapies whose complexity, length, and scarcity restricts uptake and impact.

Conditions

• Urologic Chronic Pelvic Pain Syndrome (UCPPS)
• Interstitial Cystitis
• Bladder Pain Syndrome
• Chronic Prostatitis
• Chronic Pain
• Chronic Pelvic Pain Syndrome
• Chronic Overlapping Pain Disorders

Interventions

BEHAVIORAL

Minimal Contact-Cognitive Behavior Therapy

This 4 session largely home-based version of CBT with minimal therapist contact treatment is aimed at improving UCPPS symptoms by teaching symptom self-management skills that modify illness beliefs, information processing strategies, and reactions that aggravate pelvic pain and urinary symptoms.

BEHAVIORAL

Patient Education/Support

This 4 session largely home-based treatment is aimed at improving UCPPS symptoms through the provision of support and science-based information about UCPPS symptoms, how it is diagnosed, its causes, impacts, and triggers, treatment options and a collaborative relationship between the patient and clinician.

Sponsors & Collaborators

• University of California, Los Angeles

  collaborator OTHER

• University of Michigan

  collaborator OTHER

• State University of New York at Buffalo

  lead OTHER

Principal Investigators

• Jeffrey Lackner, PsyD · University at Buffalo (SUNY)

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2022-08-10

Primary Completion

2028-02-29

Completion

2028-07-31

Countries

• United States

Study Locations