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Effect of Acidic Vaginal pH on the Efficacy of Dinoprostone for Labor Induction

NCT05100264 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 230

Last updated 2024-02-20

No results posted yet for this study

Summary

Acidification of vaginal pH has been proposed as a potential factor that could help increase the efficacy of vaginal prostaglandins in labor induction. The aim of the present randomized controlled trial is to evaluate the impact of an acidic vaginal pH on the progress of labor induction with dinoprostone (Prostaglandin E2 - PGE2) vaginal tablet.

Conditions

  • Labor, Induced
  • Induced; Birth

Interventions

OTHER

Vaginal washing with 5% acetic acid

Induction of labor (vaginal tablet dinoprostone and vaginal washing with 5% acetic acid)

OTHER

Vaginal washing with 0.9% NS

Induction of labor (vaginal tablet dinoprostone and vaginal washing 0.9% NS)

Sponsors & Collaborators

  • National and Kapodistrian University of Athens

    collaborator OTHER

  • Alexandra Hospital, Athens, Greece

    lead OTHER

Principal Investigators

  • Georgios Daskalakis · Alexandra General Hospital

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-10-29
Primary Completion
2022-12-29
Completion
2022-12-30

Countries

  • Greece

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05100264 on ClinicalTrials.gov