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Clinical & Radiographic Evaluation of LSTR in Non-vital Primary Molars Using Two Different Vehicles

NCT05079802 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2021-11-08

No results posted yet for this study

Summary

LSTR will be done for primary teeth with significant root resorption needing non-vital pulp therapy to save such teeth for up to 12 months. The first part will be in vitro study to compare the antimicrobial effect of double antibiotic paste mixed with chitosan nanoparticle vs double antibiotic paste mixed with propylene glycol. The second part will be randomized clinical trial comparing the clinical and radiographic success of LSTR in study group where double antibiotic mix is mixed with chitosan nanoparticles and control group where double antibiotic paste is mixed with propylene glycol .

Conditions

  • Resorption of Tooth or Root

Interventions

DRUG

Double antibiotic paste mixed with chitosan nanoparticles

Lesion sterilization and tissue repair in non-vital primary molars with double antibiotic paste mixed with chitosan nanoparticles gel

DRUG

Double antibiotic paste mixed with propylene glycol

Lesion sterilization and tissue repair in non-vital primary molars with double antibiotic paste mixed with propylene glycol

Sponsors & Collaborators

  • Ain Shams University

    lead OTHER

Principal Investigators

  • Olaa Abdel Geleel, PhD · Ain Shams University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
4 Years
Max Age
7 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-12-01
Primary Completion
2023-12-31
Completion
2024-03-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05079802 on ClinicalTrials.gov