Biomarker of Diabetic Retinopathy
NCT05079399 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 192
Last updated 2025-05-01
Summary
Diabetic retinopathy (DR) is a complication of diabetes in which blood vessels supplying blood to the back of the eye (retina) are dysfunctional. This can lead to an improper supply of oxygen and nutrients to the retinal tissue, or it may trigger the formation of new blood vessels in response to the oxygen/nutrient deficiency. Ultimately affecting the normal vision. There is no known marker that will provide information on the health status of retinal blood vessels. Using highly specialized cells in the blood, this study will try to discover a marker of DR.
Conditions
Interventions
- OTHER
-
Blood draw
Blood samples will be collected via venipuncture
Sponsors & Collaborators
-
Indiana University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-01-01
- Primary Completion
- 2026-06-30
- Completion
- 2026-06-30
Countries
- United States
Study Locations
More Related Trials
-
Measurement of Total Retinal Blood Flow and Oxygen Extraction in Patients With Diabetes and Healthy Subjects
NCT03552562 ·Status: RECRUITING ·Phase: NA
-
Endothelial Dysfunction and Diabetes
NCT01097551 ·Status: COMPLETED
-
Measuring Retinal Vessel Caliber in Relation to Dark Adaptation and Blood Glucose Level
NCT01136902 ·Status: COMPLETED
-
Biomarkers in Exhaled Breath of Glucose Fluctuation in Type 1 Diabetes
NCT03435198 ·Status: COMPLETED
-
Retinal Function in Relation to Long Term Changes in the Glucose Level
NCT00973401 ·Status: UNKNOWN
-
Measurement of Total Retinal Blood Flow in Patients With Diabetes and Healthy Subjects
NCT01843114 ·Status: COMPLETED ·Phase: NA
-
Vascular Reactivity in Metabolic Syndrome and Diabetic Patients Using Diffuse Optical Spectroscopy
NCT00793481 ·Status: COMPLETED
-
The Retinal Function in Relation to Glucose Changes
NCT00973726 ·Status: UNKNOWN ·Phase: NA
-
Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning in Patients With Type 1 Diabetes
NCT03906383 ·Status: COMPLETED ·Phase: NA
-
Neurovascular Coupling in Patients With Early Stage Diabetes Retinopathy
NCT00712842 ·Status: COMPLETED
-
Optical Coherence Tomography Morphologic and Fractional Flow Reserve Assessment in Diabetes Mellitus Patients
NCT02989740 ·Status: COMPLETED
-
Measurement of Eye Blood Flow and Renal Function in Healthy and Diabetic Patients
NCT01626469 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Effect of Diabetes Education During Retinal Ophthalmology Visits on Diabetes Control
NCT01323348 ·Status: COMPLETED ·Phase: PHASE3
-
Detection of Vascular Injury in Diabetes Through Eye and Nailfold Data (DIVIDEND) - A Pilot Study
NCT01279928 ·Status: COMPLETED
-
Retinal Venous Pressure and ET-1 in Patients With Diabetes Mellitus
NCT01771835 ·Status: COMPLETED
-
Retinal Function in Relation to Transient or Chronic Challenges to Retinal Metabolism
NCT01721811 ·Status: UNKNOWN ·Phase: NA
-
Development of Novel Biomarkers for the Early Diagnosis of Type 1 Diabetes
NCT04164966 ·Status: ACTIVE_NOT_RECRUITING
-
The Relationship Between Stage of Diabetic Retinopathy and Retinal Blood Flow in Patients With IDDM During Euglycemic Clamp
NCT00814008 ·Status: COMPLETED ·Phase: PHASE2
-
Diameter Changes of Retinal Vessels During Hypoxia
NCT01689090 ·Status: COMPLETED ·Phase: NA
-
Pediatric Type 1 Diabetes and Retinopathy
NCT02691312 ·Status: COMPLETED
-
Peripheral Vascular REactivity and Muscular Oxygenation in Diabetes Mellitus
NCT04226820 ·Status: RECRUITING ·Phase: NA
-
Place of Glycation in Diabetic Retinopathy
NCT05364723 ·Status: UNKNOWN
-
Microvascular Changes in OCT-angiography in Type 1 Diabetes Mellitus at the Onset of the Disease and After Optimization of Glycemic Control.
NCT04888598 ·Status: UNKNOWN
-
The Effect of Type 1 Diabetes on Pan-Arterial Vascular Function and Insulin Sensitivity in Humans
NCT02490124 ·Status: COMPLETED
-
Effect of Glucose on Ocular Blood Flow
NCT00350129 ·Status: COMPLETED