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Detection of Vascular Injury in Diabetes Through Eye and Nailfold Data (DIVIDEND) - A Pilot Study

NCT01279928 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 26

Last updated 2011-01-25

No results posted yet for this study

Summary

This project aimed to explore novel methods of detecting small blood vessel disease in a paediatric population with type 1 diabetes mellitus. To do this the techniques of Nailfold capillaroscopy, laser Doppler flowmetry, retinal (eye) vessel analysis and 24-hr Ambulatory Blood Pressure Monitoring were used. Each of these techniques investigated different areas of small blood vessels around the body.

It was hypothesized that in a paediatric population with type 1 diabetes mellitus the novel investigations would be associated with small blood vessel disease and that widespread changes to these blood vessels would be detected through associations between the different novel investigations.

Conditions

  • Type 1 Diabetes Mellitus

Interventions

PROCEDURE

Video Nailfold Capillaroscopy

Single session of video Nailfold Capillaroscopy wit KKK technology

DEVICE

Ambulatory 24 hr Blood Pressure Monitoring

24 hr upper arm cuff measurement of Blood Pressure

PROCEDURE

Fundoscopy of eyes

examination of microvascular health of eye with the use of opthalmoscope

PROCEDURE

Laser Doppler Flowmetry

Examination of vascular flow

Sponsors & Collaborators

  • John Hunter Hospital

    lead OTHER_GOV

Principal Investigators

  • Rani Bhatia, MD · John Hunter Children's Hospital

Eligibility

Min Age
8 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-03-31
Primary Completion
2010-09-30
Completion
2010-10-31

Countries

  • Australia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01279928 on ClinicalTrials.gov