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Effects of Blood Pulsatility on Von Willebrand Factor During ECCO2R

NCT05079009 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 6

Last updated 2024-05-03

No results posted yet for this study

Summary

The primary objective of the study is to demonstrate that the ECCO2R pulsatile configuration prevents the Willebrand factor high molecular weight multimers decrease observed under continuous blood flow configurations.

The secondary objectives are to quantify the CO2 extracorporeal removal in the pulsatile configuration, to describe complications (hemorrhagic, thrombotic and hemolytic), to describe patients' gas exchanges under ECCO2R, to describe the clinical course of the patients under ECCO2R as well as during the whole stay in the Intensive Care Unit (ICU).

Conditions

  • Extracorporeal CO2 Removal
  • Acute Respiratory Distress Syndrome
  • Chronic Obstructive Pulmonary Disease Exacerbation
  • Pulmonary Disease

Interventions

DEVICE

ECCO2R pulsatile configuration

Use of the pulsatile extracorporeal blood flow configuration.

Sponsors & Collaborators

  • Xenios AG

    collaborator INDUSTRY

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Jean-Luc Diehl, PhD · AP-HP, Hôpital Européen Georges Pompidou, Paris

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-01-28
Primary Completion
2023-05-16
Completion
2023-05-16

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05079009 on ClinicalTrials.gov