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Impact of Vitamine D Status on in Vitro Fertilization Outcomes

NCT05048511 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2021-09-27

No results posted yet for this study

Summary

Non skeletal effect of vitamin D have been the focus of much interest in the past decade. During the last years, special attention has been given to the impact of vitamin D on human reproduction. Its receptor is expressed in most reproductive organs including hypothalamus, pituitary gland, uterus, ovary, mammary gland and the placenta. In vitro experiments suggest that vitamin D would be involved in regulated embryo-implantation. Concerning AMH, vitamin D seems to alters AMH signaling in human granulosa cells although their circulated levels are correlated in lated reproductive aged women. The results of precedents studies about the impact of vitamin D on IVF outcomes remain conflicting The aim of our study was to assess in a large unselected population of infertile women, the impact of vitamin D deficiency on IVF outcome and to examine the relationship between serum vitamin D levels and the ovarian reserve marker AMH.

Conditions

Interventions

BIOLOGICAL

vitamin D estimation

Serum samples to estimate vitamin D status were collected on the sixth day of stimulation

Sponsors & Collaborators

  • Nantes University Hospital

    lead OTHER

Principal Investigators

  • Sophie DUBOURDIEU, Dr · Nantes University Hospital

Eligibility

Min Age
18 Years
Max Age
42 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-01-01
Primary Completion
2016-01-01
Completion
2016-01-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05048511 on ClinicalTrials.gov