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Cardiac MRI for Detection of Acute and Chronic Cardiac Involvement in Patients With Epilepsy

NCT05041296 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2021-09-13

No results posted yet for this study

Summary

The aim of the study is to use multiparametric cardiac MRI to identify any abnormalities in myocardial structure and function in patients with epilepsy. A two-stage study design is planned as part of the study:

1. In the acute setting, cardiac MRI will be performed in patients before and after a tonic-clonic seizure and compared intraindividually. In this study arm, potential acute seizure-induced myocardial damage will be detected.
2. In the chronic setting, cardiac MRI will be performed in patients with known chronic epilepsy during the seizure-free interval to detect potential chronic myocardial damage (myocardial fibrosis) and compared with a control population. Within the group of epilepsy patients, possible associations with various epilepsy-specific characteristics (e.g., form, cause, onset, duration, and severity of epilepsy) will be investigated.

Conditions

Interventions

DIAGNOSTIC_TEST

Cardiac magnetic resonance scan

Multiparametric cardiac magnetic resonance including traditional and quantitative functional and structural parameters

Sponsors & Collaborators

  • University Hospital, Bonn

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-03-07
Primary Completion
2023-12-31
Completion
2024-12-31

Countries

  • Germany

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05041296 on ClinicalTrials.gov