The Effect of Tocilizumab on Procalcitonin and Other Biochemical and Clinical Markers in the Setting of COVID-19 Pneumonia
NCT05035589 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2023-04-11
Summary
This study aims to establish whether tocilizumab has any significant effect on procalcitonin levels on patients diagnosed with COVID-19 pneumonia requiring intensive care admission. The effects on other biochemical and clinical markers are also considered.
Conditions
- COVID-19 Pneumonia
- ARDS
Interventions
- DRUG
-
Tocilizumab administered at a dose of 8mg/kg up to a maximum of 800mg
Sponsors & Collaborators
-
Mater Dei Hospital, Malta
collaborator OTHER -
Sciberras, Stephen M.D.
lead INDIV
Eligibility
- Min Age
- 16 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-09-20
- Primary Completion
- 2021-10-20
- Completion
- 2021-11-20
Countries
- Malta
Study Locations
More Related Trials
-
Mitochondrial Function in Septic Patients
NCT03748537 ·Status: COMPLETED ·Phase: NA
-
Data Analysis of the Cytokine Adsorption Treatment on Coronavirus Disease-19 (COVID-19) Patients With Respiratory Failure
NCT04422626 ·Status: WITHDRAWN
-
Impact of COVID-19 on the Incidence, Characteristics, Management and Outcome of Sepsis
NCT04698382 ·Status: WITHDRAWN
-
Effect of Citrulline on the Clinical and Biochemical Evolution of Patients With Sepsis.
NCT02370030 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Endotoxin Activity Assay and Microcirculation in Severe Sepsis
NCT02452138 ·Status: UNKNOWN
-
The Role of Myristic Acid in Serum for Early Diagnosis of Sepsis and Comparison With Selected Biomarkers of Sepsis
NCT03314831 ·Status: COMPLETED
-
Vaccine Response in Patient With Sepsis
NCT04823039 ·Status: COMPLETED ·Phase: NA
-
Nebulised Heparin in Patients With COVID-19 Pneumonia
NCT05255848 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Platelets to Lymphocytes Ratio in Sepsis
NCT05399225 ·Status: UNKNOWN
-
Early Targeted Antibiotic Therapy in Patients With Sepsis
NCT05459389 ·Status: COMPLETED ·Phase: NA
-
Zinc and Inflammation in Sepsis
NCT01328509 ·Status: COMPLETED
-
Safety and Efficacy of SCD in AKI or ARDS Patients Associated With COVID-19 Infections
NCT04395911 ·Status: COMPLETED ·Phase: NA
-
Steroids and Unfractionated Heparin in Critically Ill Patients With Pneumonia From COVID-19 Infection
NCT04528888 ·Status: UNKNOWN ·Phase: PHASE3
-
ObsErvational Study of the Practical Cinical UTility of the NuQ.® H3.1 Nucleosome Levels in Adult Patients With Sepsis to Facilitate Early Diagnosis and Prognostication. (EPICETUS)
NCT05922371 ·Status: UNKNOWN
-
Efficacy & Safety of Resatorvid in Adults With Severe Sepsis
NCT00143611 ·Status: COMPLETED ·Phase: PHASE3
-
Is Bio-adrenomedullin (Bio-ADM) a Prognostic Factor in Patients With COVID-19 Treated in the ICU?
NCT04813939 ·Status: TERMINATED
-
Epirubicin for the Treatment of Sepsis & Septic Shock
NCT05033808 ·Status: RECRUITING ·Phase: PHASE2
-
Using Biomarkers to Optimize Antibiotic Strategies in Sepsis
NCT02207114 ·Status: COMPLETED ·Phase: NA
-
Function of Circulating Exosomes in Sepsis-induced Immunosuppression
NCT04979767 ·Status: UNKNOWN
-
Treatment of COVID-19 Patients With Anti-interleukin Drugs
NCT04330638 ·Status: COMPLETED ·Phase: PHASE3
-
Clinical Trial to Evaluate CERC-002 in Adults With COVID-19 Pneumonia and Acute Lung Injury
NCT04412057 ·Status: COMPLETED ·Phase: PHASE2
-
Safety, Pharmacokinetics and Pharmacodynamics of BMS-936559 in Severe Sepsis
NCT02576457 ·Status: TERMINATED ·Phase: PHASE1
-
Clinical Study Evaluating the Efficacy and Safety of Colchicine in Adult Patients With Sepsis
NCT07074990 ·Status: COMPLETED ·Phase: NA
-
Sensitivity and Specificity of Leucocytes Profiling Versus Platelet Indices in Prediction of Clinical Outcome for Candidates With Sepsis. A Bi-centric Observational Clinical Trial
NCT06612307 ·Status: COMPLETED
-
Molecular Diagnosis and Risk Stratification of Sepsis
NCT01905033 ·Status: UNKNOWN