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Apoptosis Markers in Aggressive Periodontitis

NCT04984031 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2024-09-19

No results posted yet for this study

Summary

The aim of the present trial is to assess the gingival crevicular fluid level of caspase-3 and apoptosis inducing factor (AIF) in Generalized versus Molar-incisor grade C periodontitis.

The present study will be carried out on patients selected from those attending on the outpatient clinics of Department of Oral Medicine, Periodontology, Oral Diagnosis and Dental Radiology, Faculty of Dental Medicine, Al-Azhar University, Assiut.

Conditions

  • Molar-incisor Pattern Grade C Periodontitis ( Localized Aggressive Periodontitis)
  • Generalized Grade C Periodontitis (Generalized Aggressive Periodontitis)

Interventions

DIAGNOSTIC_TEST

ELISA assessment of apoptosis markers in gingival crevicular fluid

Gingival crevicular fluid (GCF) samples will be collected to assess the level of caspase-3,8,9 and apoptosis inducing factor (Aif)

Sponsors & Collaborators

  • Asem Mohammed Kamel Ali

    lead OTHER

Principal Investigators

  • Mohammed F Edress, associate professor · Faculty of dental medicine Al-Azhar university Assiut Branch

  • Ahmed M Hussein, phD · Oral and Maxillofacial Pathology Department, Faculty of dentistry, Assiut University

  • Ahmed H Gaber, phD · Department of oral pathology Faculty of dental medicine Al-Azhar University (Assiut branch)

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-08-05
Primary Completion
2022-01-30
Completion
2022-03-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04984031 on ClinicalTrials.gov