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Cartilage Injury and Remodeling After ACL Rupture and Reconstruction: Functional Imaging and Biomarkers

NCT04970706 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 76

Last updated 2021-07-21

No results posted yet for this study

Summary

The proposed study will establish novel relationships between intra-articular MSC recruitment, synovial inflammation, biomarkers of cartilage degeneration and joint inflammation, clinical patient factors, and downstream alterations in cartilage composition and morphology to provide novel insights into the pathoetiology of PTOA after ACL injury and reconstruction.

Conditions

  • Anterior Cruciate Ligament Injuries

Interventions

PROCEDURE

ACL reconstruction

All patients will undergo a standardized single-bundle technique with a hamstring or bone-patellar tendon-bone autograft.

Sponsors & Collaborators

Principal Investigators

  • yingfang ao, M.D. · Peking University Third Hospital

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-01
Primary Completion
2023-01-01
Completion
2023-01-01

Countries

  • China

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04970706 on ClinicalTrials.gov