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Amplification of Positivity for Alcohol Use Disorder Co-Occurring With Anxiety or Depression

NCT04934553 · Status: SUSPENDED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2022-04-20

No results posted yet for this study

Summary

The purpose of this study is to examine the feasibility of a protocol in which individuals with comorbid depression or anxiety disorders and alcohol use disorder will be randomized to complete Amplification of Positivity for Alcohol Use Disorder (AMP-A)- a psychological treatment focused on increasing positive thoughts, emotions, and behaviors- or a traditional cognitive-behavioral therapy (CBT) intervention. Assessed outcomes will include participant acceptability and completion rates, participant compliance with the intervention, positive and negative affect, substance use- and depression and anxiety-related symptom severity, and functional disability.

Conditions

  • Alcoholism
  • Alcohol Drinking
  • Drinking Behavior
  • Alcohol-Related Disorders
  • Substance-Related Disorders
  • Mental Disorder
  • Anxiety
  • Depression

Interventions

BEHAVIORAL

Amplification of Positivity Training

12 90-minute, clinician-administered treatment sessions focused on presenting rationale and instructions for completing positive activity exercises (e.g., gratitude, acts of kindness) designed to increase positive emotions, cognitions, and behaviors.

BEHAVIORAL

Cognitive-behavioral Therapy

12 90-minute, clinician-administered treatment sessions focused on strategies to alter cognitions and behavior related to alcohol use.

Sponsors & Collaborators

  • Laureate Institute for Brain Research, Inc.

    collaborator OTHER

  • Charles Taylor

    lead OTHER

Principal Investigators

  • Charles T Taylor, PhD · Altman Clinical and Translational Research Institute

  • Robin Aupperle, PhD · Laureate Institute for Brain Research

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-05-20
Primary Completion
2023-01-31
Completion
2023-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04934553 on ClinicalTrials.gov