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Comparing Behavior Therapy and Yoga for Treating Depression Among Adults

NCT05546697 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 518

Last updated 2025-11-05

No results posted yet for this study

Summary

This is a parallel group study design. The investigators propose to compare an online, synchronous group-based yoga intervention developed for individuals with depression to an online, synchronous individualized, evidence-based behavioral therapy for depression, or Brief Behavioral Activation Treatment for Depression (BA). This study is a multi-site randomized trial of adults with clinically significant depressive symptoms. Participants (N=518) will be randomized in an equal allocation ratio (i.e., 1:1) across two intervention groups: yoga and BA. Interventions will be provided over a 12-week period and assessments will occur at baseline (week 0), week 6, week 12, week 18, and week 24.

Conditions

Interventions

OTHER

Online- Yoga-based Intervetion

See arms description

BEHAVIORAL

Online- BA

See arms description

Sponsors & Collaborators

  • Butler Hospital

    collaborator OTHER

  • Hennepin Healthcare Research Institute

    collaborator OTHER

  • Medical University of South Carolina

    collaborator OTHER

  • Brown University

    collaborator OTHER

  • Wake Forest University Health Sciences

    collaborator OTHER

  • Massachusetts General Hospital

    lead OTHER

Principal Investigators

  • Louisa Sylvia, PhD · Massachusetts General Hospital

  • Lisa Uebelacker, PhD · Butler Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-02-13
Primary Completion
2026-05-01
Completion
2026-05-01

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05546697 on ClinicalTrials.gov