Efficacy of Titanium Granules in the Treatment of Periodontal Intrabony Defects
NCT04932161 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2021-06-21
Summary
The ideal goal of the periodontal treatment is not only to prevent the progression of the disease, but also the regeneration and reconstruction of lost tissues. Many surgical techniques have been used to regenerate intrabony defects (IBD).
Titanium stimulates activation of the complement system, surface binding of platelets, and platelet activation as reflected by increased levels of platelet-derived growth factor, which is a substantial promoter of bone growth. Hence we may speculate that using a bone substitute made of titanium may be positive from the perspective of bone formation in osseous defects.
Conditions
- Intrabony Periodontal Defect
Interventions
- PROCEDURE
-
Titanium Granules
After degranulation of the intrabony defect, titanium particles will be placed in the defect and will be sutured.
- PROCEDURE
-
Hydroxyapatite
After degranulation of the intrabony defect, hydroxyapatite will be placed in the defect and will be sutured.
Sponsors & Collaborators
-
SVS Institute of Dental Sciences
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-08-31
- Primary Completion
- 2022-02-28
- Completion
- 2022-12-31
Countries
- India
Study Locations
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