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Comparison of MIST With PRF and GBT With PRF in the Treatment of Intrabony Periodontal Defect. A Prospective RCT

NCT06768424 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2026-04-28

No results posted yet for this study

Summary

The aim is to evaluate in a prospective, randomized, controlled clinical study the healing of a MIST procedure combined with PRF, or GBT combined with PRF. Clinical, radiological evaluation of the regenerative surgical method and the GBT non-surgical therapy in solitaire deep intrabony periodontal defect.

Conditions

  • Intrabony Periodontal Defect

Interventions

DEVICE

Guided biofilm therapy

Use of Airflow Plus powder subgingivally on teeth with deep periodeontal pockets

PROCEDURE

Platelet Rich Fibrin

Pack Platelet Rich Fibrin chops into the intrabony periodontla defect

PROCEDURE

Minimally Invasive Surgical Technique

Periodontal intrabony defect is treated by minimally invasive surgical intervention

Sponsors & Collaborators

  • Semmelweis University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-12-20
Primary Completion
2027-06-30
Completion
2027-12-20

Countries

  • Hungary

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06768424 on ClinicalTrials.gov