OPtical Diagnosis Training to Improve Dysplasia Characterisation in IBD

Summary

People with inflammatory bowel diseases (IBD) can be at higher risk of developing abnormal areas in their bowel. These abnormal areas can be due to active inflammation, healed inflammation, polyps or pre-cancerous changes ("dysplasia"). It is for this reason that people with IBD are offered periodic surveillance colonoscopy procedures to identify, characterize and where necessary remove abnormal areas or lesions from the bowel. These can be difficult to characterize correctly, which is important to make the correct endoscopic diagnosis and management plan. Technical advancements in endoscopy mean that more tools are available to identify and characterize these lesions in real time during colonoscopy. Specialists regularly performing gastrointestinal endoscopy and colonoscopy ("endoscopists") will often receive special training, both during their initial postgraduate training and through continuous professional development programs.

This study aims to evaluate whether an online training platform can improve the ability of endoscopists to characterize dysplasia in IBD. The goal is to support improved decision-making during IBD surveillance, reporting of dysplastic lesions, and ultimately the care and outcomes of people with IBD.

Conditions

• Inflammatory Bowel Diseases
• Dysplasia Colon
• Dysplasia, Crohn Disease-Associated
• Polyp of Colon
• Ulcerative Colitis
• Crohn Colitis
• Crohn Disease

Interventions

OTHER

Online self-learning training module

Training module in optical diagnosis of IBD-associated dysplastic lesions during gastrointestinal endoscopy

OTHER

Refresher training

Brief refresher training in optical diagnosis of IBD-associated dysplastic lesions during gastrointestinal endoscopy

Sponsors & Collaborators

• University of Calgary

  collaborator OTHER

• University of Milan

  collaborator OTHER

• Federico II University

  collaborator OTHER

• University of Bari Aldo Moro

  collaborator OTHER

• University of Birmingham

  lead OTHER

Principal Investigators

• Marietta Iacucci, MD PhD · University of Birmingham

• Jose G Ferraz, MD PhD · University of Calgary

• Gian E Tontini, MD PhD · University of Milan

Study Design

Allocation

RANDOMIZED

Purpose

OTHER

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

65 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2021-07-07

Primary Completion

2021-12-20

Completion

2022-04-30

Countries

• Canada
• Italy
• United Kingdom

Study Locations