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Chromoendoscopy for Dysplasia Detection in Chronic Inflammatory Bowel Disease

NCT01505842 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 304

Last updated 2019-03-06

No results posted yet for this study

Summary

Patients with longstanding ulcerative colitis or crohn's disease in the large bowel have an increased risk of developing cancer. The purpose of this study is to determine if visualizing of the mucosa in details using a dye spray (indigo-carmine) will result in detection of more abnormalities than conventional colonoscopy without dye spray.

Conditions

Interventions

PROCEDURE

Colonoscopy with Indigo-Carmine chromoendoscopy

Colonoscopy with chromoendoscopy using 0.2-0.5% Indigo-Carmine solution sprayed in the whole colon and rectum plus 32 random biopsies plus biopsies from suspicious areas

PROCEDURE

Conventional white-light colonoscopy

White light colonoscopy plus 32 random biopsies plus biopsies from suspicious areas

Sponsors & Collaborators

  • Karolinska University Hospital

    lead OTHER

Principal Investigators

  • Peter T Schmidt, MD, PhD · Karolinska University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-02-28
Primary Completion
2019-04-04
Completion
2019-04-04

Countries

  • Sweden

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01505842 on ClinicalTrials.gov