Clinical Outcome of Autonomous Cortisol Secretion in Adrenal Incidentalomas
NCT04917757 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 3656
Last updated 2025-09-05
Summary
The primary aim of the study is to assess mortality and cardiovascular events potentially linked to cortisol excess in patients with adrenal incidentalomas stratified by cortisol values following the 1-mg overnight dexamethasone test.
Conditions
- Adrenal Incidentaloma
Interventions
- DIAGNOSTIC_TEST
-
1mg Dexamethasone test
For each patient a 1mg dexamethasone test has been performed.
Sponsors & Collaborators
-
European Network for the Study of Adrenal Tumors
collaborator OTHER_GOV -
Wuerzburg University Hospital
lead OTHER
Principal Investigators
-
Martin Fassnacht, MD · Wuerzburg University Hospital
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-01-01
- Primary Completion
- 2019-08-31
- Completion
- 2025-12-31
Countries
- Germany
- Italy
Study Locations
More Related Trials
-
Study on the Incidence of Adrenal Insufficiency After Surgery in Primary Aldosteronism Patients Concurrent With or Without Autonomous Cortisol Secretion
NCT06955286 ·Status: RECRUITING
-
Peri-Operative Steroid Management in Patients
NCT02084134 ·Status: COMPLETED ·Phase: NA
-
Determination of Method-specific Normal Cortisol and Adrenal Hormone Responses to the Short Synacthen Test
NCT00851942 ·Status: COMPLETED ·Phase: PHASE4
-
Safety and Efficacy of Different Dose Levels of Pasireotide in Patients With de Novo, Persistent or Recurrent Cushing's Disease
NCT00434148 ·Status: COMPLETED ·Phase: PHASE3
-
Hair Cortisol and Cushing's Disease
NCT04201444 ·Status: COMPLETED ·Phase: NA
-
Setting Benchmarks for Transsphenoidal Resection of Pituitary Adenomas
NCT04951557 ·Status: UNKNOWN
-
Unilateral Primary Aldosteronism, Mineralocorticoid Antagonists Versus Surgical Treatment
NCT05797558 ·Status: RECRUITING ·Phase: NA
-
Predictive Factors of Response to Somatostatin Analogues in Acromegalic Patients With Persistent Disease Following Surgery
NCT00500227 ·Status: COMPLETED
-
Effect of Vorinostat on ACTH Producing Pituitary Adenomas in Cushing s Disease
NCT04339751 ·Status: WITHDRAWN ·Phase: PHASE2
-
Updated Diagnostic Cortisol Values for Adrenal Insufficiency
NCT05149638 ·Status: RECRUITING ·Phase: NA
-
Test Predicting Adrenal Insufficiency in Volunteers Under Prednisone Treatment
NCT00975078 ·Status: COMPLETED ·Phase: PHASE4
-
Study and Monitoring of Multiple Endocrine Neoplasia Type 1
NCT03966612 ·Status: RECRUITING
-
Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome
NCT01246739 ·Status: TERMINATED ·Phase: NA
-
COrticosteroid in Congenital Adrenal Hyperplasia
NCT02552251 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Efficacy and Safety of Lanreotide Autogel (60, 90 or 120 mg) in Acromegalic Patients
NCT00210457 ·Status: COMPLETED ·Phase: PHASE3
-
Non-interventional Study on Osilodrostat in Patients With Endogenous Cushing's Syndrome
NCT05382156 ·Status: ACTIVE_NOT_RECRUITING
-
Study of the Efficacy and Safety of Pasireotide s.c. +/- Cabergoline in Patients With Cushing's Disease
NCT01915303 ·Status: TERMINATED ·Phase: PHASE2
-
Efficacy and Safety of Pasireotide Administered Monthly in Patients With Cushing's Disease
NCT01374906 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome
NCT03697109 ·Status: COMPLETED ·Phase: PHASE3
-
Congenital Adrenal Hyperplasia Once Daily Hydrocortisone Treatment
NCT03760835 ·Status: RECRUITING ·Phase: PHASE4
-
Effect of Adrenocorticotropic Hormone Stimulation During Adrenal Vein Sampling in Primary Aldosteronism
NCT05826080 ·Status: UNKNOWN
-
The Factors Associated With the Recurrence in Patients With Cushing Disease
NCT02233335 ·Status: COMPLETED
-
The Influence of Different Hydrocortisone Replacement Doses on the Partitioning and Flexibility of Ectopic Lipids in Patients With Corticotropic Hypopituitarism
NCT02360046 ·Status: TERMINATED ·Phase: NA
-
Development of Clinical Evidence for Optimal Management of Adrenal Diseases Based on Real-World Data
NCT06229405 ·Status: RECRUITING
-
Short-term gluCOCOrticoid in Adult STEROID-sensitive Nephrotic Syndrome: The COCO-ASTEROID Study
NCT07151456 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4