Metabolite Levels in Ovarian Cancer Patients Receiving Maintenance PARP Inhibitors
NCT04917744 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 5
Last updated 2025-04-03
Summary
This study evaluates blood samples and compares levels of metabolites (levels of vitamins, carbohydrates, proteins, etc., that are in the blood), before and after the plasma exchange in patients scheduled to receive immunotherapy for their ovarian cancer. The information gained from this study may help researchers better understand the side effects from each treatment and possibly lessen those side effects for future treatments.
Conditions
- Ovarian Carcinoma
Interventions
- PROCEDURE
-
Biospecimen Collection
Undergo collection of blood samples
- OTHER
-
Laboratory Biomarker Analysis
Ancillary studies
- OTHER
-
Medical Chart Review
Review of medical charts
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Jacob J. Orme, M.D., Ph.D. · Mayo Clinic in Rochester
Eligibility
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-04-01
- Primary Completion
- 2023-04-17
- Completion
- 2024-02-17
Countries
- United States
Study Locations
More Related Trials
-
Evaluation of Metformin, Targeting Cancer Stem Cells for Prevention of Relapse in Gynecologic Patients
NCT01579812 ·Status: COMPLETED ·Phase: PHASE2
-
Maveropepimut-S (MVP-S) and Low-Dose CPA in Patients With Platinum-Resistant Ovarian Cancer
NCT05243524 ·Status: TERMINATED ·Phase: PHASE2
-
Genetic Landscape in Women with Metastatic Ovarian Cancer Before and During Treatment with PARP Inhibitors
NCT06785077 ·Status: RECRUITING ·Phase: NA
-
Biomarkers in Patients With Previously Untreated Invasive Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
NCT01295489 ·Status: COMPLETED
-
Study of Pembrolizumab With or Without CC-486 in Patients With Platinum-resistant Ovarian Cancer
NCT02900560 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Safety & Biological Activity of IP IMNN-001 (also Known As GEN-1) with Neoadjuvant Chemo in Ovarian Cancer
NCT02480374 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Paclitaxel, Carboplatin and Oral Metformin in the Treatment of Advanced Stage Ovarian Carcinoma
NCT02437812 ·Status: UNKNOWN ·Phase: PHASE2
-
PARPi and Ovarian Cancer Survival
NCT06838429 ·Status: NOT_YET_RECRUITING
-
Dysregulation of Whole-body Metabolism in Ovarian Cancer: A Longitudinal Study
NCT06800105 ·Status: RECRUITING
-
Pembrolizumab and Lenvatinib in Clear Cell Ovarian Cancer
NCT05296512 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Phase 1 Study of NY-ESO-1 Overlapping Peptides in Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT00616941 ·Status: COMPLETED ·Phase: PHASE1
-
Pembrolizumab, Bevacizumab, and Cyclophosphamide in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT02853318 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Chemotherapy IV Carboplatin With Weekly Paclitaxel \Bevacizumab for Primary Ovarian
NCT01219777 ·Status: COMPLETED ·Phase: PHASE1
-
Carboplatin, Gemcitabine Hydrochloride, and Berzosertib in Treating Patients With Recurrent and Metastatic Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
NCT02627443 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer
NCT05071937 ·Status: RECRUITING ·Phase: PHASE2
-
The Effect of Glucose Level and Diabetes Mellitus on Ctrough of Olaparib
NCT05081765 ·Status: UNKNOWN
-
Impact of Dietary Patterns on Prognosis of Ovarian Cancer Patients During PARPi Maintenance
NCT07269574 ·Status: NOT_YET_RECRUITING
-
MUC1-Activated T Cells for the Treatment of Relapsed and Resistant Ovarian Cancer
NCT06483048 ·Status: RECRUITING ·Phase: PHASE1
-
Retrospective Case Study to Validate Existing Chemoresponse Marker Test in Ovarian, Peritoneal or Fallopian Cancer Cases
NCT01048814 ·Status: COMPLETED
-
A Study of IMP4297 as Maintenance Treatment Following First-line Chemotherapy in Patients With Advanced Ovarian Cancer
NCT04169997 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Efficacy Study of Maintenance IT-101 Therapy for Ovarian Cancer Patients.
NCT00753740 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Study to Evaluate rhuMab 2C4 and Gemcitabine in Subjects With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
NCT00096993 ·Status: COMPLETED ·Phase: PHASE2
-
Study on the Dynamic Changes of Metabolic Biomarkers and Their Prognostic Relationship in Ovarian Cancer
NCT06019923 ·Status: RECRUITING
-
Safety and Efficacy of Intraperitoneal Injection of METR-NK Cells as Neoadjuvant Therapy for Advanced Epithelial Ovarian Cancer
NCT06395844 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Study of Lenalidomide With Topotecan In Subjects With Advanced Ovarian and Primary Peritoneal Carcinoma
NCT00179712 ·Status: COMPLETED ·Phase: PHASE1/PHASE2