GPED for Patients With Relapsed/Refractory or Advanced NK/T-cell Lymphoma
NCT04917250 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2021-06-08
Summary
The purpose of this study is to evaluate the efficacy and safety of GPED (gemcitabine, pegaspargase, etoposide, and dexamethasone) regimen in the treatment of Relapsed/Refractory or advanced NK/T-cell lymphoma patients
Conditions
- Extranodal NK/T-cell Lymphoma
Interventions
- DRUG
-
1000mg/㎡,d1,4 ivdrip
- DRUG
-
Pegaspargase
2500IU/㎡, maximum dose less than 3750IU
- DRUG
-
Etoposide
100mg/㎡,d1-3 ivdrip
- DRUG
-
20mg/d d1-4 ivdrip
Sponsors & Collaborators
-
Beijing Tongren Hospital
lead OTHER
Principal Investigators
-
Liang Wang, M.D. · Beijing Tongren Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 16 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-03-20
- Primary Completion
- 2021-06-30
- Completion
- 2021-08-31
Countries
- China
Study Locations
More Related Trials
-
S0350 Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Peripheral T-Cell Non-Hodgkin's Lymphoma
NCT00109928 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine, Cisplatin, and Dexamethasone in Treating Patients With Relapsed or Refractory Hodgkin's Lymphoma
NCT00090909 ·Status: COMPLETED ·Phase: PHASE2
-
A Pilot Study of Oncaspar® + Dexamethasone in Patients With Relapsed or Refractory T-Cell Lymphoma
NCT01878708 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
A Phase II Study of Dexamethasone, Azacitidine, Pegaspargase and Tislelizumab Plus Radiotherapy for Patients With Stage I/II Extranodal NK/T-cell Lymphoma
NCT07000617 ·Status: RECRUITING ·Phase: PHASE2
-
GELAD Chemotherapy and Sandwiched Radiotherapy in the Treatment of Stage IE/IIE Natural Killer/T-cell Lymphoma
NCT02733458 ·Status: COMPLETED ·Phase: NA
-
Mitoxantrone Hydrochloride Liposomes in Combination With GDP in Relapsed/Refractory PTCL
NCT05441761 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Biweekly Gemcitabine-Oxaliplatin and Dexamethasone for Relapsed/Refractory Malignant Lymphoma
NCT00561301 ·Status: UNKNOWN ·Phase: PHASE2
-
Study on the Combination Regimen of Dexamethasone Ifosfamide Cisplatin Etoposide in Patients With NK/T Cell Lymphoma
NCT00568607 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of Sugemalimab (or Placebo) Plus PGemOx Regimen in Participants With Extranodal NK/T-Cell Lymphoma
NCT05700448 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
GAD-M Regimen As First-Line Treatment in Untreated Extranodal NK/T Cell Lymphoma
NCT01991158 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of GFH009 Monotherapy in Patients with Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)
NCT05934513 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Nivolumab in Combination With GDP/ L-asparaginase in NK/ T-cell Lymphoma
NCT04230330 ·Status: WITHDRAWN ·Phase: PHASE1
-
Ifosfamide, Carboplatin, Etoposide, and SGN-30 in Treating Young Patients With Recurrent Anaplastic Large Cell Lymphoma
NCT00354107 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Cisplatin With Gemcitabine With Dexamethasone in Patients With Aggressive Non-Hodgkin's Lymphoma
NCT00491127 ·Status: COMPLETED ·Phase: PHASE2
-
Etoposide in Treating Patients With Relapsed Non-Hodgkin's Lymphoma
NCT00002880 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Including Cisplatin, Ifosfamide, Gemcitabine, L-asparaginase, Etoposide and Dexamethasone as Treatment of Newly Diagnosed and Relapsed/Refractory Peripheral T Cell Lymphomas
NCT03071822 ·Status: UNKNOWN ·Phase: PHASE4
-
Study of HMPL-760 Plus R-GemOx Versus Placebo Plus R-GemOx in Relapsed/Refractory DLBCL
NCT06601504 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Combination of Basiliximab and Pegaspargase in the Treatment of ENKTCL
NCT04337593 ·Status: UNKNOWN ·Phase: PHASE2
-
Evaluating the Effectiveness of Decitabine With Gemcitabine, Oxaliplatin for Relapsed/Refractory Peripheral T-cell Lymphoma
NCT06941688 ·Status: TERMINATED ·Phase: PHASE2
-
Phase I Study of Romidepsin, Gemcitabine, Oxaliplatin, and Dexamethasone in Patients With Relapsed/Refractory Aggressive Lymphomas
NCT02181218 ·Status: COMPLETED ·Phase: PHASE1
-
Chemotherapy Based on Positron Emission Tomography Scan in Treating Patients With Stage I or Stage II Hodgkin Lymphoma
NCT01132807 ·Status: COMPLETED ·Phase: PHASE2
-
Romidepsin, Gemcitabine, Dexamethasone and Cisplatin in the Treatment of Peripheral T-Cell and Diffuse Large B-Cell Lymphoma
NCT01846390 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy of EX103 in Subjects with Relapsed/Refractory CD20-Positive Non-Hodgkin Lymphoma
NCT06021678 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Phase II Study VEPEMB In Patients With Hodgkin's Lymphoma Aged ≥ 60 Years
NCT00079105 ·Status: COMPLETED ·Phase: PHASE2
-
Chidamide + R-GemOx Regimen as Salvage Treatment for Transplant-ineligible Patients With Relapsed/Refractory DLBCL
NCT04022005 ·Status: COMPLETED ·Phase: PHASE2