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Restenosis in Coronary Stents And Cutaneous HEaLing

NCT04915391 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2022-11-21

No results posted yet for this study

Summary

Case control study of patients with and without restenosis to demonstrate the link between in-stent restenosis and an excessive skin healing. Patients will undergo skin biopsy and blood sample tests to search for a relationship between both processes and for the identification of biomarkers and therapeutic targets.

Conditions

  • Coronary Restenosis
  • Coronary Stent Occlusion
  • Skin Scarring
  • Keloid

Interventions

DIAGNOSTIC_TEST

Skin biopsy and blood sample for inflammation markers, RNA and proteins

A skin biopsy will be performed at the baseline visit from which primary cell cultures of fibroblasts and keratinocytes will be obtained. Four to six weeks later a second biopsy on the scar will be performed and analyzed anatomically and pathologically. In addition, at the initial visit, blood samples will be drawn for analysis of inflammation markers, RNA and proteins.

Sponsors & Collaborators

  • Fundación para la Investigación Biosanitaria del Principado de Asturias

    lead OTHER

Principal Investigators

  • Iñigo Lozano, MD, PHD · Hospital Cabuenes

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-04-25
Primary Completion
2022-12-31
Completion
2023-04-30

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04915391 on ClinicalTrials.gov