Flow Patterns and Stent Thrombosis

Summary

The goal of this observational study is to study the effect of haemodynamic forces on thrombus formation and identify haemodynamic markers that predict stent thrombosis events in patients who have undergone OCT-guided percutaneous coronary interventions.

The primary objective of the study is to examine the efficacy of blood flow patterns in predicting stent thrombosis. Researchers will compare the blood flow patterns of the stent thrombosis group with that of the control group to understand the influence of blood flow patterns on thrombus formation and progression.

Conditions

• Stent Thrombosis

Sponsors & Collaborators

• Barts Helth NHS Trust

  collaborator UNKNOWN

• Oxford University Hospitals NHS Trust

  collaborator OTHER

• Royal Free Hospital NHS Foundation Trust

  collaborator OTHER

• University Hospitals Bristol and Weston NHS Foundation Trust

  collaborator OTHER

• Mid and South Essex NHS Foundation Trust

  collaborator OTHER

• Newcastle-upon-Tyne Hospitals NHS Trust

  collaborator OTHER

• Liverpool Heart and Chest Hospital NHS Foundation Trust

  collaborator OTHER

• Manchester University NHS Foundation Trust

  collaborator OTHER_GOV

• King's College Hospital NHS Trust

  collaborator OTHER

• San Giovanni Addolorata Hospital

  collaborator OTHER

• Medstar Health Research Institute

  collaborator OTHER

• Medical University of Warsaw

  collaborator OTHER

• Insel Gruppe AG, University Hospital Bern

  collaborator OTHER

• Hospital San Carlos, Madrid

  collaborator OTHER

• The Leeds Teaching Hospitals NHS Trust

  collaborator OTHER

• McMaster University Health Sciences Centre

  collaborator UNKNOWN

• Fujita Health University

  collaborator OTHER

• Harbin Medical University

  collaborator OTHER

• Yale University

  collaborator OTHER

• Fundación de Investigación Biomédica - Hospital Universitario de La Princesa

  collaborator OTHER

• Erasmus Medical Center

  collaborator OTHER

• Radbound University Medical Center

  collaborator UNKNOWN

• Department of Cardiovascular Surgery, German Heart Center Munich

  collaborator UNKNOWN

• Columbia University

  collaborator OTHER

• The Queen Elizabeth Hospital

  collaborator OTHER

• Yonsei University Hospital, Seoul, South Korea

  collaborator UNKNOWN

• Nara Medical University

  collaborator OTHER

• Shinshu University School of Medicine

  collaborator UNKNOWN

• University Hospitals Sussex NHS Foundation Trust

  collaborator UNKNOWN

• Galeazzi Sant'Ambrogio Hospital - Milan

  collaborator UNKNOWN

• CORRIB Core Lab, University of Galway

  collaborator UNKNOWN

• Queen Mary University of London

  lead OTHER

Eligibility

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-04-01

Primary Completion

2026-07-14

Completion

2026-07-14

Countries

• United Kingdom

Study Locations