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The Senstivity and Specificity of Using Salivary miRNAs in Detection of Malignant Transformation of Oral Lesions.

NCT04913545 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 18

Last updated 2021-06-09

No results posted yet for this study

Summary

Due to cancer is a leading cause of death world wide , we will coduct the study to evaluate the diagnostic accuracy of using salivary miRNAs (412,512) from the salivary extracellular vesicles (index test) in detection of the malignant transformation of the premalignant lesions using the qualitative real time polymerase chain reaction (qRT-PCR) analysis in comparison to taking biopsy .

Conditions

  • Oral Premalignant Lesions

Interventions

DIAGNOSTIC_TEST

using salivary miRNA (412,512)

quantitative real time polymerase chain reaction to detect the salivary miRNAs 412,512) to indicate the malignant transformation in potientially malignant oral lesions.

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • Ghareeb · Assistant lecturer

Eligibility

Min Age
35 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-06-05
Primary Completion
2020-01-07
Completion
2020-08-07

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04913545 on ClinicalTrials.gov