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Diagnostic and Prognostic Accuracy of Gold Nanoparticles in Salivary Gland Tumours

NCT04907422 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2021-09-01

No results posted yet for this study

Summary

Nano-based diagnostic tool can provide promising highly sensitive, specific biomarker for early detection and treatment of salivary gland tumours compared to non-conjugated biomarkers and in turn improves patient prognosis and outcome.

Conditions

  • Carcinoma Ex Pleomorphic Adenoma of Salivary Glands
  • Pleomorphic Adenoma of Salivary Glands

Interventions

DIAGNOSTIC_TEST

CD24-Gold Nanocomposite expression using Real-time quantitative polymerase chain reaction

new strategy where gold nanoparticles synthetized and added to CD24 primer forming CD24-Gold Nanocomposite to be used for detection of cancer stem cells

DIAGNOSTIC_TEST

non-conjugated CD24 expression using Real-time quantitative polymerase chain reaction

conventional strategy using non-conjugated CD24 expression to used for detection of cancer stem cells

Sponsors & Collaborators

  • Amina Fouad Farag

    lead OTHER

Principal Investigators

  • Amina F Farag, PhD · Faculty of Dentistry, October 6 University

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-08-06
Primary Completion
2019-02-03
Completion
2021-02-03

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04907422 on ClinicalTrials.gov