MedTrace Logo

Somatotopy in Parkinson's Disease

NCT04876404 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2024-10-26

No results posted yet for this study

Summary

This study aims to assess changes in connections within the brain in Parkinson's disease (PD). We will invite up to 10 people with PD to participate in this study and complete several brain scans using PET (Positron Emission Tomography) and fMRI (functional Magnetic Resonance Imaging) on the Hybrid PET/MRI scanner. We will also invite 10 participants without PD to complete the same scans for comparison. "Somatotopy" refers to how areas of the brain are organized according to the body part they affect. The striatum is the brain region that coordinates complex thinking and movement. Plasticity refers to changes in connections within the brain, which can happen to make up for changes that are related to PD. In this study we will use PET and fMRI imaging together to investigate changes in the striatum in people affected by Parkinson's disease. The hybrid PET/MR scanner allows us to perform simultaneous PET and MRI measurements to investigate this.

Conditions

  • Parkinson Disease

Interventions

DIAGNOSTIC_TEST

PET/MR Imaging

The hybrid PET/MR scanner can provide information on brain activity during various motor and cognitive tasks.

Sponsors & Collaborators

  • University of British Columbia

    collaborator OTHER

  • Pacific Parkinson's Research Centre

    lead OTHER

Principal Investigators

  • Jess McKenzie · Pacific Parkinson's Research Centre

Eligibility

Min Age
50 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-25
Primary Completion
2023-11-27
Completion
2024-08-01

Countries

  • Canada

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04876404 on ClinicalTrials.gov