Clinical, Molecular and Metabolic Characteristics of Parkinson's Disease (PD) Patients With Parkin Mutation
NCT00169364 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2007-08-29
Summary
Parkinson's disease is a frequent neurodegenerative disorder. Genetic forms of the disease have been recently identified. The monogenic form due to parkin mutation is responsible for many familial cases and sporadic forms. However, the relationship between the mutation and the genotype of patients is not fully established. The aim of this study is to compare clinical, metabolic and neuropsychological characteristics obtained in patients with parkin mutation with those of patients without parkin mutation.
Conditions
Interventions
- DEVICE
-
positron emission tomography
Sponsors & Collaborators
-
University Hospital, Tours
collaborator OTHER -
Groupe Hospitalier Pitie-Salpetriere
lead OTHER
Principal Investigators
-
Alexis Brice, MD, PhD · Groupe Hospitalier Pitié-Salpêtrière
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2002-05-31
Countries
- France
Study Locations
More Related Trials
-
Serotonin Release in Premotor and Motor PD
NCT05516732 ·Status: RECRUITING
-
Neuroplasticity in Parkinson's Disease
NCT05286736 ·Status: RECRUITING
-
Somatotopy in Parkinson's Disease
NCT04876404 ·Status: COMPLETED
-
PET Imaging in Parkinson Disease Dementia
NCT01052350 ·Status: ACTIVE_NOT_RECRUITING
-
The Differential Diagnosis of Parkinson's Disease and Parkinsonism by Positron-emission Tomography
NCT01824056 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of Clinical Progression in Patients With Motor Predominant Parkinson Disease.
NCT03960242 ·Status: TERMINATED
-
Evaluation of a Multimodal Neuroimaging Method for Diagnosis in Parkinsonian Syndromes
NCT02428816 ·Status: COMPLETED ·Phase: NA
-
Early Biomarkers of Neurodegeneration in Parkinsonian Syndromes
NCT06155942 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Measure of Microglial Activation in the Brain of Parkinson Disease Patients With PET
NCT02319382 ·Status: UNKNOWN ·Phase: NA
-
Compensation Mechanisms in Parkinson's Disease
NCT02869945 ·Status: COMPLETED ·Phase: NA
-
Parkin Mutations and Their Functional Consequences
NCT00136721 ·Status: COMPLETED
-
Development of a Novel 18F-DTBZ PET Imaging as a Biomarker to Monitor Neurodegeneration of PARK6 and PARK8 Parkinsonism
NCT01759888 ·Status: COMPLETED ·Phase: PHASE2
-
Exploratory Study of the Expression of the Serotonergic 5-HT4 Receptor in Parkinson's Disease
NCT05916625 ·Status: COMPLETED ·Phase: NA
-
Predictive Value of Multimodal MRI in Parkinson's Disease
NCT05003206 ·Status: UNKNOWN ·Phase: NA
-
PET/MR Imaging in Patients With Short and Long Standing Parkinson's Disease
NCT02801110 ·Status: UNKNOWN
-
Motor Skill Learning in People With Parkinson's Disease
NCT00396942 ·Status: COMPLETED
-
Cohort Study to Identify Predictor Factors of Onset and Progression of Parkinson's Disease
NCT02305147 ·Status: RECRUITING
-
Comparison Between Parkinson's Disease and Parkinson's Dementia Complex (Genetically,Clinical and Electrophysiological)
NCT05759403 ·Status: UNKNOWN
-
Genotypic Influences on Network Progression in Parkinson's Disease
NCT04228172 ·Status: ACTIVE_NOT_RECRUITING
-
Positron Emission Tomography (PET) Imaging in People With Gaucher Mutations
NCT00302146 ·Status: COMPLETED
-
PET Imaging Study of Neurochemical and Autonomic Disorders in Multiple System Atrophy (MSA)
NCT02035761 ·Status: COMPLETED
-
Investigating the Microstructural and Functional Alterations of Brain in Parkinson's Disease Patients
NCT02599753 ·Status: COMPLETED ·Phase: PHASE2
-
Cognitive Testing Online in Parkinson's Disease
NCT05025254 ·Status: RECRUITING
-
Non-motor Symptoms and Brain Dopamine Transporter Binding
NCT02650843 ·Status: ACTIVE_NOT_RECRUITING
-
Molecular and Functional Imaging in SNCA, Parkin and PINK1
NCT04084509 ·Status: WITHDRAWN