Cognitive Trance, Hypnosis and Meditation in Oncology

Summary

Patients with cancer often suffer from a symptom cluster, including pain, fatigue, sleep difficulties, emotional distress and cognitive impairments. In oncology settings, there is a growing interest in "mind-body" intervention, to relieve them in a non-pharmacological way. Hypnosis and meditation are two modified state of consciousness shown to positively this symptom cluster. Cognitive trance is also a modified state of consciousness, but is induced by body movements and/or vocalizations. Subjective reports of experts in cognitive trance showed a modification of self, emotion regulation, pain perception, attention and concentration. However, we still need to develop studies to better characterise this particular state of consciousness and its clinical applications. Our randomized-controlled trial aims at comparing both interventions in terms of (1) benefits on cancer patients' quality of life (pain, fatigue, sleep, distress, cognitive impairments), (2) phenomenological/subjective experiences and neurophysiological correlates, and (3) mechanisms involved in patients' responsiveness, based on the biopsychosocial model of hypnosis.

Conditions

• Cancer
• Distress, Emotional
• Pain
• Fatigue
• Sleep Disturbance
• Cognitive Impairment

Interventions

BEHAVIORAL

Hypnosis group intervention

See arm description

BEHAVIORAL

Cognitive trance group intervention

See arm description

BEHAVIORAL

Meditation group intervention

See arm description

Sponsors & Collaborators

• FNRS (Télévie)

  collaborator UNKNOWN

• Fondation contre le cancer

  collaborator UNKNOWN

• Bial Foundation

  collaborator UNKNOWN

• Centre Hospitalier Universitaire de Liege

  collaborator OTHER

• University of Liege

  lead OTHER

Principal Investigators

• Olivia Gosseries, PhD · ULiège

Study Design

Allocation

NON_RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2021-01-01

Primary Completion

2025-07-31

Completion

2025-07-31

Countries

• Belgium

Study Locations