Scottish Vitamin D Intervention Study
NCT04868227 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2025-01-24
Summary
AIMS To identify the underlying mechanism by which Vitamin D reduces colorectal cancer risk.
OBJECTIVES To demonstrate the effects of vitamin D supplementation on serum vitamin D levels.
To demonstrate dynamic changes in gene expression in response to vitamin D. To demonstrate the mechanism underlying the gene-environment interaction of vitamin D, susceptibility genetic variants (risk genes) and colorectal cancer.
Conditions
- GENE EXPRESSION
- Colorectal Cancer
Interventions
- DIETARY_SUPPLEMENT
-
FULTIUM D3 VITAMIN D3
VITAMIN D3 SUPPLEMENT
Sponsors & Collaborators
- collaborator OTHER
- collaborator OTHER_GOV
-
University of Edinburgh
lead OTHER
Principal Investigators
-
Malcolm G Dunlop, MD · MRC HGU University of Ediniburgh
Study Design
- Allocation
- NA
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-03-28
- Primary Completion
- 2016-04-11
- Completion
- 2016-07-11
Countries
- United Kingdom
Study Locations
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