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Use of Dual Energy Computed Tomography in Thoracic Radiotherapy Planning.

NCT04863027 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2022-11-16

No results posted yet for this study

Summary

This is a prospective observational study aiming: 1) To quantify lung function using perfusion dual energy computed tomography (DECT) and use this information at the time of treatment planning with preferential sparing of functional lung parenchymal 2) to validate results of lung function obtained using DECT with lung perfusion scintigraphy results, the current standard method; 4) to compare dosimetry of whole lungs vs. functional lungs in patients treated with either stereotactic body radiotherapy (SBRT) for early stage lung cancer or conventional radiotherapy for locally advanced lung cancer and 5) to evaluate lung function 6, 12 and 24 months post-radiotherapy with both perfusion DECT and pulmonary function tests and compare radiation dose-map to functional lung-map.

Conditions

  • Lung Cancer
  • Lung Function Decreased
  • Radiation Pneumonitis

Interventions

RADIATION

Thoracic radiotherapy

Patients will have pre-treatment and post-treatment perfusion DECT for baseline and post-treatment lung function

Sponsors & Collaborators

  • Varian Medical Systems

    collaborator INDUSTRY

  • Centre hospitalier de l'Université de Montréal (CHUM)

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-31
Primary Completion
2022-11-30
Completion
2022-11-30

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04863027 on ClinicalTrials.gov