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Determinants of Successful Decannulation in Difficult-to-wean Patients

NCT04841889 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2024-02-29

No results posted yet for this study

Summary

The factors of success of decannulation are not well known in the literature and the decision to decannulate is mainly based on clinical judgment. The failure rate of decannulation is between 2 and 25% with a poor prognosis in case of failure.

The objective of this study is to determine the factors associated with successful tracheostomy removal in patients hospitalized in a respiratory weaning unit.

The secondary objectives are to evaluate in tracheostomized and hospitalized patients in weaning unit:

* The prevalence of successful tracheostomy removal;
* The prevalence of successful weaning from mechanical ventilation;
* Factors associated with successful weaning from mechanical ventilation;
* Demographic characteristics of these patients at admission;
* Ventilatory characteristics of these patients at admission;
* Biological characteristics of these patients at admission;

This is a prospective, single-centre, interventional cohort study with an expected duration of 2 years. All patients admitted to the respiratory weaning unit in the Forcilles' hospital, with a tracheostomy and an expected duration of mechanical ventilation \> 48 hours will be consecutively included.

All factors potentially associated with successful tracheostomy removal will be prospectively collected: severity factors related to the ICU stay, ventilatory factors, respiratory and extra-respiratory factors.

Conditions

  • Tracheostomy
  • ICU
  • Weaning Failure

Interventions

DIAGNOSTIC_TEST

Associated factors with decannulation

All factors potentially associated with successful tracheostomy removal will be prospectively collected: severity factors related to the ICU stay, ventilatory factors, respiratory and extra-respiratory factors. Lung and diaphragm ultrasound, swallowing, muscles and functional assessment will be performed.

Sponsors & Collaborators

  • Hopital Forcilles

    lead OTHER

Principal Investigators

  • PERETOUT Jean-Baptiste, MD · Hôpital Forcilles-Fondation Cognacq-Jay

Study Design

Allocation
NA
Purpose
SCREENING
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-04-15
Primary Completion
2023-04-15
Completion
2023-04-15

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04841889 on ClinicalTrials.gov