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Peri-implantitis in HIV-positive Patients

NCT04829968 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 58

Last updated 2021-04-02

No results posted yet for this study

Summary

Objectives: This study aimed to assess the prevalence of peri-implantitis in human im-munodeficiency virus (HIV) -positive patients and the presence of a possible correlation between the immunological profile and serological values, of peri-implantitis, and of pos-sible differences between all-on-4 and single crown/bridge prostheses.

Subjects and methods: This retrospective study included 58 adult HIV-positive patients (222 implants) with either all-in-4 prostheses or single crowns/bridges on at least one dental implant loaded for more than a year who were followed for at least one year. Data pertaining to the probing pocket depth (PPD), bleeding on probing, and immunological and systemic profile were collected.

Results: Patients with single crown/bridge implant rehabilitation showed higher preva-lence of peri-implantitis (34%) than patients with all-on-4 rehabilitation (0%) (p=0.012). Patients with all-on-4 rehabilitation were significantly older than those with single crowns/bridges (p=0.004). Patients with peri-implantitis had implants for a significantly longer duration than those without (p=0.001), implying that the probability of peri-implantitis increases as the age of implant increases.

Conclusions: The prevalence of peri-implantitis was 26% in HIV-positive patients and 8% in dental implants. No correlation was found between patients' immunological and se-rological factors and peri-implantitis. The most important risk factor for peri-implantitis and mucositis was implant age.

Conditions

  • Peri-Implantitis

Interventions

OTHER

gingival conditions control

Peri-implant mucositis: It was diagnosed on the basis of the following criteria: 1. Visual inspection demonstrating the following signs of inflammation in the peri-implant region: red as opposed to pink colour, swollen tissues as opposed to no swelling, and soft as opposed to firm tissue consistency. 2. Presence of profuse (line or drop) bleeding and/or suppuration on probing. 3. An increase in probing pocket depths (PPDs) compared to baseline. • Peri-implantitis: It was diagnosed on the basis of the following criteria: 1\. Visual inflammatory changes in the peri-implant soft tissues combined with bleeding on probing and/or suppuration. 2\. Increasing PPDs as compared to measurements recorded at the time of placement of supra-structures.

Sponsors & Collaborators

  • Università Vita-Salute San Raffaele

    lead OTHER

Eligibility

Sex
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-01
Primary Completion
2019-11-01
Completion
2019-11-30

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04829968 on ClinicalTrials.gov