9 Minutes for Tandem Colonoscopy Withdrawal

Summary

A mean withdrawal time of at least 6 minutes has been considered to be one of the critical quality criterions of colonoscopy. Recently, our group completed a multicenter randomized controlled trial, which proved that prolonging the withdrawal time to 9 minutes could significantly improve the adenoma detection rate of colonoscopists, especially for young colonoscopists and proximal colon. However, it has some limitations in included participates (mixed indications for colonoscopy) and cannot illustrate the impact of withdrawal time on adenoma miss rate in a parallel randomized design. It is necessary to include tandem colonoscopy and adopt strict criteria of the screening population to confirm the effect of the 9-minute withdrawal time on the adenoma miss rate. Therefore, the investigators plan to conduct a multicenter, randomized controlled trial of tandem colonoscopy to compare adenoma miss rate of 6-minute and 9-minute withdrawal in screening population.

Conditions

• Colon Polyp
• Colorectal Adenoma

Interventions

PROCEDURE

6-minute then 9-minute withdrawal

Patients in 6-minute then 9-minute withdrawal group will first be carefully observed in 2 minutes then in 3 minutes during each colonic segment. In actual performance, withdrawal of the right colon, transverse colon and the left colon can be operated in segmental tandem colonoscopy. Taking the right colon as an example, after the endoscope reaches the cecum, it can be withdrawn to the splenic curvature in 2 minutes, then reentered the cecum and withdrawn to the splenic curvature in 3 minutes.

PROCEDURE

9-minute then 6-minute withdrawal

Patients in 9-minute then 6-minute withdrawal group will first be carefully observed in 3 minutes then in 2 minutes during each colonic segment. In actual performance, withdrawal of the right colon, transverse colon and the left colon can be operated in segmental tandem colonoscopy. Taking the right colon as an example, after the endoscope reaches the cecum, it can be withdrawn to the splenic curvature in 3 minutes, then reentered the cecum and withdrawn to the splenic curvature in 2 minutes.

Sponsors & Collaborators

• No.85 Hospital, Changning, Shanghai, China

  collaborator OTHER

• Yantaishan Hospital of Yantai City, Yantai, China

  collaborator UNKNOWN

• Seventh Medical Center of PLA Army General Hospital

  collaborator OTHER

• The First Affiliated Hospital of Dalian Medical University

  collaborator OTHER

• The First Affiliated Hospital of the Medical College, Shihezi University

  collaborator UNKNOWN

• Shanghai 8th People's Hospital

  collaborator OTHER

• Shanxi Provincial People's Hospital

  collaborator OTHER_GOV

• Qinghai People's Hospital

  collaborator OTHER

• Leqing People's Hospital

  collaborator UNKNOWN

• Affiliated Hospital of North Sichuan Medical College

  collaborator OTHER

• Zhejiang University

  collaborator OTHER

• Songjiang Hospital Affiliated to Shanghai Jiaotong University School of Medicine

  collaborator OTHER_GOV

• The General Hospital of Eastern Theater Command

  collaborator OTHER

• Heilongjiang provincial hospital

  collaborator UNKNOWN

• The Second Hospital of Hebei Medical University

  collaborator OTHER

• Changhai Hospital

  lead OTHER

Principal Investigators

• Zhaoshen Li, M.D · Changhai Hospital

Study Design

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

SINGLE

Model

CROSSOVER

Eligibility

Min Age

40 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2021-03-01

Primary Completion

2021-11-05

Completion

2021-12-05

Countries

• China

Study Locations