MedTrace Logo

Activation of Apoptosis-related Receptors on Alveolar Macrophages

NCT04775394 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2023-08-01

No results posted yet for this study

Summary

The aim is to understand whether activation of receptors involved in clearance of apoptotic cells will improve efferocytosis in COPD patients in vitro and whether generation of pro-inflammatory cytokines can be decreased in COPD patients.

Conditions

Interventions

OTHER

Bronchoscopy

Bronchoalveolar lavage, mucosal biopsy and bronchial brushes during bronchoscopy

Sponsors & Collaborators

  • Prof. Dr. Jens Hohlfeld

    lead OTHER

Principal Investigators

  • Jens M Hohlfeld, Prof. Dr. · Fraunhofer ITEM Hannover, Germany

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SEQUENTIAL

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-01
Primary Completion
2023-07-21
Completion
2023-07-21

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04775394 on ClinicalTrials.gov