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Dose the Saline Reduce the Mucus Production When Water Exchange Colonoscopy is Used?

NCT04769739 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 301

Last updated 2024-01-05

Study results available
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Summary

This is a study to compare the left colon mucus production between carbon dioxide (CO2) insufflation and water exchange (WE) colonoscopy in patients that require a routine or repeat colonoscopy. There will be four arms in this study: CO2 insufflation (control group 1), WE with water infusion (control group 2), WE with 50% saline infusion (study group 1), and WE with 25% saline infusion (study group 2). The patient will prepare himself/herself for the colonoscopy as per normal instructions and he/she will be given the information for the study at that time so that he/she can make a decision to participate in the study. The WE control group will use sterile water filling during colonoscope insertion. The study method will use saline filling during colonoscopy insertion. This study will confirm if using the saline infusion is a better method in reducing mucus production when WE colonoscopy is used.

Conditions

  • Colon Mucous
  • Colonoscopy

Interventions

OTHER

CO2

using CO2 insufflation to help insertion

OTHER

Water

using water instead of traditional gas to help insertion

OTHER

50% saline

using 50% saline solution instead of traditional gas to help insertion

OTHER

25% saline

using 25% saline solution instead of traditional gas to help insertion

Sponsors & Collaborators

  • Evergreen General Hospital, Taiwan

    lead OTHER

Principal Investigators

  • Chiliang Cheng, MD · Evergreen General Hospital, Taoyuan, Taiwan

Study Design

Allocation
RANDOMIZED
Purpose
SCREENING
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-08-04
Primary Completion
2022-03-23
Completion
2022-04-30

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04769739 on ClinicalTrials.gov