Comparison of Dexmedetomidine and Meperidine for the Prevention of Shivering Following Coronary Artery Bypass Graft
NCT04735965 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 180
Last updated 2022-01-10
Summary
This study aims to compare the effects of dexmedetomidine and meperidine on the incidence of shivering in patients undergoing CABG.
Conditions
- Coronary Artery Disease
- Postoperative Shivering
Interventions
- DRUG
-
Dexmedetomidine
Dexmedetomidine would be intravenously infused at a dose of 1μg/kg over 15 minutes 30 min before the end of surgery
- DRUG
-
Meperidine
Meperidine would be intravenously injected at a dose of 0.5mg/kg 30 min before the end of surgery
- DRUG
-
Placeb
Equal volume of normal saline to dexmedetomidine and meperidine group.
Sponsors & Collaborators
-
Qianfoshan Hospital
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-07-15
- Primary Completion
- 2022-07-31
- Completion
- 2022-08-31
Countries
- China
Study Locations
More Related Trials
-
Comparative Study Between the Efficacy of Intravenous Hydrocortisone and Intravenous Dexmedetomidine for Prevention of Postoperative Shivering After General Anaesthesia for Abdominal Surgeries
NCT07154849 ·Status: RECRUITING ·Phase: PHASE4
-
Perioperative Dexmedetomidine and 30-Day Outcomes After Adult Cardiac Surgery
NCT07249164 ·Status: COMPLETED
-
Remifentanil Versus Dexmedetomidine for Post-Cardiac Surgery Patients With Noninvasive Ventilation Intolerance
NCT03395886 ·Status: COMPLETED
-
Efficacy of Intrathecal Versus Intravenous Dexmedetomidine for Prevention of Post Spinal Anesthesia Shivering
NCT02965586 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Protective Effects of Dexmedetomidine on Myocardial Injury During Liver Transplantation
NCT03013634 ·Status: UNKNOWN ·Phase: NA
-
Dexmedetomidine and Myocardial Protection
NCT04871308 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Dexmedetomidine Versus Clonidine to Control Delirium in Patients Undergoing CABG
NCT03477994 ·Status: COMPLETED ·Phase: NA
-
Dexmedetomidine Versus Morphine and Midazolam in Prevention and Treatment of Delirium After Adult Cardiac Surgery
NCT03078946 ·Status: COMPLETED ·Phase: PHASE4
-
A Comparative Study Between Dexmedetomidine Versus Methylprednisolone on Induced Inflammatory Response in Patients Undergoing On-pump CABG
NCT07101367 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Efficacy of Intravenous Nefopam, Dexmedetomidine, and Meperidine in Preventing Post-Spinal Anesthesia Shivering in Adult Patients Undergoing Lower Abdominal and Lower Limb Surgeries.
NCT06627816 ·Status: COMPLETED ·Phase: NA
-
Dexmedetomidine for the Treatment of Delirium After Heart Surgery
NCT01140529 ·Status: TERMINATED ·Phase: PHASE3
-
Prophylactic Mirtazapine or Dexamethasone for Post-spinal Anesthesia Shivering
NCT03675555 ·Status: COMPLETED ·Phase: PHASE4
-
Evaluation of Remifentanil and Dexmedetomidine in Patients With Noninvasive Mechanical Ventilation Intolerance
NCT04734418 ·Status: UNKNOWN ·Phase: NA
-
Dexmedetomidine and Outcomes of Cardiac Surgery (DOCS)
NCT02237495 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Prevention of Post-Operative Cardiac Arrhythmias
NCT04234906 ·Status: UNKNOWN ·Phase: PHASE4
-
Intravenous Dexmedetomidine Versus Midazolam in Preventing Shivering in Trauma Patients Undergoing Lower Limb Orthopedic Surgery Under Spinal Anesthesia
NCT07300826 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Dexmedetomidine and IV Acetaminophen for the Prevention of Postoperative Delirium Following Cardiac Surgery
NCT02546765 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Dexmedetomidine and Propofol on Regional Cerebral Tissue Oxygen Saturation
NCT03817112 ·Status: COMPLETED ·Phase: NA
-
Intrathecal Dexmedetomidine Versus Intrathecal Morphine Inpatients Undergoing Cardiac Valve Replacement Surgeries
NCT06076759 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effect of Dexmedetomidine on Central Nervous System Complications in Patients Undergoing Cardiac Surgery
NCT06551259 ·Status: COMPLETED ·Phase: PHASE4
-
A Research Study to Evaluate the Effectiveness of Dexmedetomidine in Preventing Delirium After Heart Surgery
NCT00464763 ·Status: WITHDRAWN ·Phase: PHASE3
-
Dexmedetomidine and Fentanyl As Adjuvants to Hyperbaric Bupivacaine for the Prevention of Post-spinal Shivering in Hip Arthroplasty Surgeries
NCT06834841 ·Status: RECRUITING ·Phase: NA
-
Intravenous Dexmedetomidine For The Quaity Of Emergence From General Anesthesia
NCT02141412 ·Status: COMPLETED ·Phase: PHASE4
-
Dexmedetomidine for Pain Reduction in CABG
NCT05534230 ·Status: UNKNOWN ·Phase: NA
-
Dexmedetomidine's Cardiac and Cognitive Influence on Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery
NCT01704092 ·Status: UNKNOWN