Dexmedetomidine for Pain Reduction in CABG
NCT05534230 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2022-09-09
Summary
The purpose of this study is to determine whether adjuvant intravenous dexmedetomidine infusion starting after induction of general anesthesia can provide superior pain management (decrease pain scores) and decrease opioid administration, without increasing nausea/vomiting, compared to patients receiving only opioid and acetaminophen for the patients which going through coronary artery bypass grafting (CABG)?
Conditions
- Analgesia
Interventions
- DRUG
-
Dexmedetomidine Injectable Solution
Intravenous dexmedetomidine infusion started after induction at a standard dose of 0.5mcg/kg/hr and continued until extubation.
- DRUG
-
Saline
Intravenous normal saline at a standard dose of 0.5mcg/kg/hr continued to postop until extubation.
Sponsors & Collaborators
-
Wayne State University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- SUPPORTIVE_CARE
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-09-06
- Primary Completion
- 2023-07-10
- Completion
- 2024-05-09
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